Kaye PT - Search Results

1

Synthesis and evaluation of 3-hydroxy-3-phenylpropanoate ester–AZT conjugates as potential dual-action HIV-1 Integrase and Reverse Transcriptase inhibitors.

Manyeruke MH, Olomola TO, Majumder S, Abrahams S, Isaacs M, Mautsa N, Mosebi S, Mnkandhla D, Hewer R, Hoppe HC, Klein R, Kaye PT. Manyeruke MH, et al. Among authors: kaye pt. Bioorg Med Chem. 2015 Dec 15;23(24):7521-8. doi: 10.1016/j.bmc.2015.10.039. Bioorg Med Chem. 2015. PMID: 26775541

2

Synthesis and evaluation of coumarin derivatives as potential dual-action HIV-1 protease and reverse transcriptase inhibitors.

Olomola TO, Klein R, Mautsa N, Sayed Y, Kaye PT. Olomola TO, et al. Among authors: kaye pt. Bioorg Med Chem. 2013 Apr 1;21(7):1964-71. doi: 10.1016/j.bmc.2013.01.025. Epub 2013 Jan 22. Bioorg Med Chem. 2013. PMID: 23415084

3

Novel furocoumarins as potential HIV-1 integrase inhibitors.

Olomola TO, Mosebi S, Klein R, Traut-Johnstone T, Coates J, Hewer R, Kaye PT. Olomola TO, et al. Among authors: kaye pt. Bioorg Chem. 2014 Dec;57:1-4. doi: 10.1016/j.bioorg.2014.07.008. Epub 2014 Jul 30. Bioorg Chem. 2014. PMID: 25159595

4

Synthesis and evaluation of substituted 4-(N-benzylamino)cinnamate esters as potential anti-cancer agents and HIV-1 integrase inhibitors.

Faridoon, Edkins AL, Isaacs M, Mnkandhla D, Hoppe HC, Kaye PT. Faridoon, et al. Among authors: kaye pt. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3810-2. doi: 10.1016/j.bmcl.2016.05.023. Epub 2016 May 9. Bioorg Med Chem Lett. 2016. PMID: 27317645

5

Synthesis and antimalarial activity of N-benzylated (N-arylcarbamoyl)alkylphosphonic acid derivatives.

Adeyemi CM, Faridoon, Isaacs M, Mnkandhla D, Hoppe HC, Krause RW, Kaye PT. Adeyemi CM, et al. Among authors: kaye pt. Bioorg Med Chem. 2016 Dec 1;24(23):6131-6138. doi: 10.1016/j.bmc.2016.04.021. Epub 2016 Apr 9. Bioorg Med Chem. 2016. PMID: 27773366

6

Application of the Morita-Baylis-Hillman reaction in the synthesis of 3-[(N-cycloalkylbenzamido)methyl]-2-quinolones as potential HIV-1 integrase inhibitors.

Sekgota KC, Majumder S, Isaacs M, Mnkandhla D, Hoppe HC, Khanye SD, Kriel FH, Coates J, Kaye PT. Sekgota KC, et al. Among authors: kaye pt. Bioorg Chem. 2017 Dec;75:310-316. doi: 10.1016/j.bioorg.2017.09.015. Epub 2017 Sep 22. Bioorg Chem. 2017. PMID: 29080495

7

Synthesis and evaluation of substituted 4-arylimino-3-hydroxybutanoic acids as potential HIV-1 integrase inhibitors.

Faridoon, Mnkandhla D, Isaacs M, Hoppe HC, Kaye PT. Faridoon, et al. Among authors: kaye pt. Bioorg Med Chem Lett. 2018 Apr 1;28(6):1067-1070. doi: 10.1016/j.bmcl.2018.02.020. Epub 2018 Feb 12. Bioorg Med Chem Lett. 2018. PMID: 29482943

8

Synthesis and biological evaluation of bis-N²,N²'-(4-hydroxycoumarin-3-yl)ethylidene]-2,3-dihydroxysuccinodihydrazides.

Manyeruke MH, Tshiwawa T, Hoppe HC, Isaacs M, Seldon R, Warner DF, Krause RWM, Kaye PT. Manyeruke MH, et al. Among authors: kaye pt. Bioorg Med Chem Lett. 2020 Mar 1;30(5):126911. doi: 10.1016/j.bmcl.2019.126911. Epub 2019 Dec 19. Bioorg Med Chem Lett. 2020. PMID: 31952962

9

Synthesis and biological evaluation of 2-chloro-3-[(thiazol-2-yl)amino]-1,4-naphthoquinones.

Olawode EO, Tandlich R, Prinsloo E, Isaacs M, Hoppe H, Seldon R, Warner DF, Steenkamp V, Kaye PT. Olawode EO, et al. Among authors: kaye pt. Bioorg Med Chem Lett. 2019 Jul 1;29(13):1572-1575. doi: 10.1016/j.bmcl.2019.05.001. Epub 2019 May 3. Bioorg Med Chem Lett. 2019. PMID: 31080006

10

Synthesis and anti-parasitic activity of achiral N-benzylated phosphoramidic acid derivatives.

Adeyemi CM, Conibear AC, Mutorwa MK, Nokalipa IC, Isaacs M, Mnkandhla D, Hoppe HC, Lobb KA, Klein R, Kaye PT. Adeyemi CM, et al. Among authors: kaye pt. Bioorg Chem. 2020 Aug;101:103947. doi: 10.1016/j.bioorg.2020.103947. Epub 2020 May 16. Bioorg Chem. 2020. PMID: 32559578

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