Xu W - Search Results

1

Production of New Cladosporin Analogues by Reconstitution of the Polyketide Synthases Responsible for the Biosynthesis of this Antimalarial Agent.

Cochrane RV, Sanichar R, Lambkin GR, Reiz B, Xu W, Tang Y, Vederas JC. Cochrane RV, et al. Among authors: xu w. Angew Chem Int Ed Engl. 2016 Jan 11;55(2):664-8. doi: 10.1002/anie.201509345. Epub 2015 Nov 24. Angew Chem Int Ed Engl. 2016. PMID: 26783060 Free PMC article.

2

Structural analysis of protein-protein interactions in type I polyketide synthases.

Xu W, Qiao K, Tang Y. Xu W, et al. Crit Rev Biochem Mol Biol. 2013 Mar-Apr;48(2):98-122. doi: 10.3109/10409238.2012.745476. Epub 2012 Dec 19. Crit Rev Biochem Mol Biol. 2013. PMID: 23249187 Free PMC article. Review.

3

LovG: the thioesterase required for dihydromonacolin L release and lovastatin nonaketide synthase turnover in lovastatin biosynthesis.

Xu W, Chooi YH, Choi JW, Li S, Vederas JC, Da Silva NA, Tang Y. Xu W, et al. Angew Chem Int Ed Engl. 2013 Jun 17;52(25):6472-5. doi: 10.1002/anie.201302406. Epub 2013 May 7. Angew Chem Int Ed Engl. 2013. PMID: 23653178 Free PMC article.

4

Comparison of 10,11-Dehydrocurvularin Polyketide Synthases from Alternaria cinerariae and Aspergillus terreus Highlights Key Structural Motifs.

Cochrane RV, Gao Z, Lambkin GR, Xu W, Winter JM, Marcus SL, Tang Y, Vederas JC. Cochrane RV, et al. Among authors: xu w. Chembiochem. 2015 Nov;16(17):2479-83. doi: 10.1002/cbic.201500428. Epub 2015 Oct 23. Chembiochem. 2015. PMID: 26493380 Free PMC article.

5

Understanding Programming of Fungal Iterative Polyketide Synthases: The Biochemical Basis for Regioselectivity by the Methyltransferase Domain in the Lovastatin Megasynthase.

Cacho RA, Thuss J, Xu W, Sanichar R, Gao Z, Nguyen A, Vederas JC, Tang Y. Cacho RA, et al. Among authors: xu w. J Am Chem Soc. 2015 Dec 23;137(50):15688-91. doi: 10.1021/jacs.5b11814. Epub 2015 Dec 10. J Am Chem Soc. 2015. PMID: 26630357 Free PMC article.

6

Acyltransferase mediated polyketide release from a fungal megasynthase.

Xie X, Meehan MJ, Xu W, Dorrestein PC, Tang Y. Xie X, et al. Among authors: xu w. J Am Chem Soc. 2009 Jun 24;131(24):8388-9. doi: 10.1021/ja903203g. J Am Chem Soc. 2009. PMID: 19530726 Free PMC article.

7

Analysis of intact and dissected fungal polyketide synthase-nonribosomal peptide synthetase in vitro and in Saccharomyces cerevisiae.

Xu W, Cai X, Jung ME, Tang Y. Xu W, et al. J Am Chem Soc. 2010 Oct 6;132(39):13604-7. doi: 10.1021/ja107084d. J Am Chem Soc. 2010. PMID: 20828130 Free PMC article.

8

Crystal structure and biochemical studies of the trans-acting polyketide enoyl reductase LovC from lovastatin biosynthesis.

Ames BD, Nguyen C, Bruegger J, Smith P, Xu W, Ma S, Wong E, Wong S, Xie X, Li JW, Vederas JC, Tang Y, Tsai SC. Ames BD, et al. Among authors: xu w. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11144-9. doi: 10.1073/pnas.1113029109. Epub 2012 Jun 25. Proc Natl Acad Sci U S A. 2012. PMID: 22733743 Free PMC article.

9

Characterization of a silent azaphilone gene cluster from Aspergillus niger ATCC 1015 reveals a hydroxylation-mediated pyran-ring formation.

Zabala AO, Xu W, Chooi YH, Tang Y. Zabala AO, et al. Among authors: xu w. Chem Biol. 2012 Aug 24;19(8):1049-59. doi: 10.1016/j.chembiol.2012.07.004. Chem Biol. 2012. PMID: 22921072 Free PMC article.

10

Methylation-dependent acyl transfer between polyketide synthase and nonribosomal peptide synthetase modules in fungal natural product biosynthesis.

Zou Y, Xu W, Tsunematsu Y, Tang M, Watanabe K, Tang Y. Zou Y, et al. Among authors: xu w. Org Lett. 2014 Dec 19;16(24):6390-3. doi: 10.1021/ol503179v. Epub 2014 Dec 10. Org Lett. 2014. PMID: 25494235 Free PMC article.

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