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Page 1
Molecular Determinants of GS-9620-Dependent TLR7 Activation.
Rebbapragada I, Birkus G, Perry J, Xing W, Kwon H, Pflanz S. Rebbapragada I, et al. Among authors: birkus g. PLoS One. 2016 Jan 19;11(1):e0146835. doi: 10.1371/journal.pone.0146835. eCollection 2016. PLoS One. 2016. PMID: 26784926 Free PMC article.
Inhibition of hepatitis C virus replication by GS-6620, a potent C-nucleoside monophosphate prodrug.
Feng JY, Cheng G, Perry J, Barauskas O, Xu Y, Fenaux M, Eng S, Tirunagari N, Peng B, Yu M, Tian Y, Lee YJ, Stepan G, Lagpacan LL, Jin D, Hung M, Ku KS, Han B, Kitrinos K, Perron M, Birkus G, Wong KA, Zhong W, Kim CU, Carey A, Cho A, Ray AS. Feng JY, et al. Among authors: birkus g. Antimicrob Agents Chemother. 2014;58(4):1930-42. doi: 10.1128/AAC.02351-13. Epub 2014 Jan 13. Antimicrob Agents Chemother. 2014. PMID: 24419349 Free PMC article.
GS-9191 is a novel topical prodrug of the nucleotide analog 9-(2-phosphonylmethoxyethyl)guanine with antiproliferative activity and possible utility in the treatment of human papillomavirus lesions.
Wolfgang GH, Shibata R, Wang J, Ray AS, Wu S, Doerrfler E, Reiser H, Lee WA, Birkus G, Christensen ND, Andrei G, Snoeck R. Wolfgang GH, et al. Among authors: birkus g. Antimicrob Agents Chemother. 2009 Jul;53(7):2777-84. doi: 10.1128/AAC.00103-09. Epub 2009 Apr 27. Antimicrob Agents Chemother. 2009. PMID: 19398642 Free PMC article.
Metabolism and pharmacokinetics of the anti-hepatitis C virus nucleotide prodrug GS-6620.
Murakami E, Wang T, Babusis D, Lepist EI, Sauer D, Park Y, Vela JE, Shih R, Birkus G, Stefanidis D, Kim CU, Cho A, Ray AS. Murakami E, et al. Among authors: birkus g. Antimicrob Agents Chemother. 2014;58(4):1943-51. doi: 10.1128/AAC.02350-13. Epub 2014 Jan 13. Antimicrob Agents Chemother. 2014. PMID: 24419340 Free PMC article.
GS-9219--a novel acyclic nucleotide analogue with potent antineoplastic activity in dogs with spontaneous non-Hodgkin's lymphoma.
Reiser H, Wang J, Chong L, Watkins WJ, Ray AS, Shibata R, Birkus G, Cihlar T, Wu S, Li B, Liu X, Henne IN, Wolfgang GH, Desai M, Rhodes GR, Fridland A, Lee WA, Plunkett W, Vail D, Thamm DH, Jeraj R, Tumas DB. Reiser H, et al. Among authors: birkus g. Clin Cancer Res. 2008 May 1;14(9):2824-32. doi: 10.1158/1078-0432.CCR-07-2061. Clin Cancer Res. 2008. PMID: 18451250
56 results