Sommese RF - Search Results

1

Effects of hypertrophic and dilated cardiomyopathy mutations on power output by human β-cardiac myosin.

Spudich JA, Aksel T, Bartholomew SR, Nag S, Kawana M, Yu EC, Sarkar SS, Sung J, Sommese RF, Sutton S, Cho C, Adhikari AS, Taylor R, Liu C, Trivedi D, Ruppel KM. Spudich JA, et al. Among authors: sommese rf. J Exp Biol. 2016 Jan;219(Pt 2):161-7. doi: 10.1242/jeb.125930. J Exp Biol. 2016. PMID: 26792326 Free PMC article. Review.

2

Helicity of short E-R/K peptides.

Sommese RF, Sivaramakrishnan S, Baldwin RL, Spudich JA. Sommese RF, et al. Protein Sci. 2010 Oct;19(10):2001-5. doi: 10.1002/pro.469. Protein Sci. 2010. PMID: 20669185 Free PMC article.

3

Molecular consequences of the R453C hypertrophic cardiomyopathy mutation on human β-cardiac myosin motor function.

Sommese RF, Sung J, Nag S, Sutton S, Deacon JC, Choe E, Leinwand LA, Ruppel K, Spudich JA. Sommese RF, et al. Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12607-12. doi: 10.1073/pnas.1309493110. Epub 2013 Jun 24. Proc Natl Acad Sci U S A. 2013. PMID: 23798412 Free PMC article.

4

Effects of troponin T cardiomyopathy mutations on the calcium sensitivity of the regulated thin filament and the actomyosin cross-bridge kinetics of human β-cardiac myosin.

Sommese RF, Nag S, Sutton S, Miller SM, Spudich JA, Ruppel KM. Sommese RF, et al. PLoS One. 2013 Dec 18;8(12):e83403. doi: 10.1371/journal.pone.0083403. eCollection 2013. PLoS One. 2013. PMID: 24367593 Free PMC article.

5

Mechanistic heterogeneity in contractile properties of α-tropomyosin (TPM1) mutants associated with inherited cardiomyopathies.

Gupte TM, Haque F, Gangadharan B, Sunitha MS, Mukherjee S, Anandhan S, Rani DS, Mukundan N, Jambekar A, Thangaraj K, Sowdhamini R, Sommese RF, Nag S, Spudich JA, Mercer JA. Gupte TM, et al. Among authors: sommese rf. J Biol Chem. 2015 Mar 13;290(11):7003-15. doi: 10.1074/jbc.M114.596676. Epub 2014 Dec 29. J Biol Chem. 2015. PMID: 25548289 Free PMC article.

6

Mechanical coordination in motor ensembles revealed using engineered artificial myosin filaments.

Hariadi RF, Sommese RF, Adhikari AS, Taylor RE, Sutton S, Spudich JA, Sivaramakrishnan S. Hariadi RF, et al. Among authors: sommese rf. Nat Nanotechnol. 2015 Aug;10(8):696-700. doi: 10.1038/nnano.2015.132. Epub 2015 Jul 6. Nat Nanotechnol. 2015. PMID: 26149240 Free PMC article.

7

Establishing disease causality for a novel gene variant in familial dilated cardiomyopathy using a functional in-vitro assay of regulated thin filaments and human cardiac myosin.

Pan S, Sommese RF, Sallam KI, Nag S, Sutton S, Miller SM, Spudich JA, Ruppel KM, Ashley EA. Pan S, et al. Among authors: sommese rf. BMC Med Genet. 2015 Oct 26;16:97. doi: 10.1186/s12881-015-0243-5. BMC Med Genet. 2015. PMID: 26498512 Free PMC article.

8

Contractility parameters of human β-cardiac myosin with the hypertrophic cardiomyopathy mutation R403Q show loss of motor function.

Nag S, Sommese RF, Ujfalusi Z, Combs A, Langer S, Sutton S, Leinwand LA, Geeves MA, Ruppel KM, Spudich JA. Nag S, et al. Among authors: sommese rf. Sci Adv. 2015 Oct 9;1(9):e1500511. doi: 10.1126/sciadv.1500511. eCollection 2015 Oct. Sci Adv. 2015. PMID: 26601291 Free PMC article.

9

Engineering Synthetic Myosin Filaments Using DNA Nanotubes.

Sommese RF, Sivaramakrishnan S. Sommese RF, et al. Methods Mol Biol. 2018;1805:93-101. doi: 10.1007/978-1-4939-8556-2_5. Methods Mol Biol. 2018. PMID: 29971714

10

Engineering Synthetic Myosin Filaments Using DNA Nanotubes.

Debrunner IS, Sommese RF, Sivaramakrishnan S. Debrunner IS, et al. Among authors: sommese rf. Methods Mol Biol. 2025;2881:157-166. doi: 10.1007/978-1-0716-4280-1_8. Methods Mol Biol. 2025. PMID: 39704943

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