Yuan K - Search Results

1

Identification of initial leads directed at the calmodulin-binding region on the Src-SH2 domain that exhibit anti-proliferation activity against pancreatic cancer.

Tzou YM, Bailey SK, Yuan K, Shin R, Zhang W, Chen Y, Singh RK, Shevde LA, Krishna NR. Tzou YM, et al. Among authors: yuan k. Bioorg Med Chem Lett. 2016 Feb 15;26(4):1237-44. doi: 10.1016/j.bmcl.2016.01.027. Epub 2016 Jan 12. Bioorg Med Chem Lett. 2016. PMID: 26803204 Free PMC article.

2

Calmodulin mediates Fas-induced FADD-independent survival signaling in pancreatic cancer cells via activation of Src-extracellular signal-regulated kinase (ERK).

Yuan K, Jing G, Chen J, Liu H, Zhang K, Li Y, Wu H, McDonald JM, Chen Y. Yuan K, et al. J Biol Chem. 2011 Jul 15;286(28):24776-84. doi: 10.1074/jbc.M110.202804. Epub 2011 May 25. J Biol Chem. 2011. PMID: 21613217 Free PMC article.

3

Calmodulin antagonists promote TRA-8 therapy of resistant pancreatic cancer.

Yuan K, Yong S, Xu F, Zhou T, McDonald JM, Chen Y. Yuan K, et al. Oncotarget. 2015 Sep 22;6(28):25308-19. doi: 10.18632/oncotarget.4490. Oncotarget. 2015. PMID: 26320171 Free PMC article.

4

PARP-1 regulates resistance of pancreatic cancer to TRAIL therapy.

Yuan K, Sun Y, Zhou T, McDonald J, Chen Y. Yuan K, et al. Clin Cancer Res. 2013 Sep 1;19(17):4750-9. doi: 10.1158/1078-0432.CCR-13-0516. Epub 2013 Jul 5. Clin Cancer Res. 2013. PMID: 23833311 Free PMC article.

5

Reduced CaM/FLIP binding by a single point mutation in c-FLIP(L) modulates Fas-mediated apoptosis and decreases tumorigenesis.

Jing G, Yuan K, Liang Q, Sun Y, Mao X, McDonald JM, Chen Y. Jing G, et al. Among authors: yuan k. Lab Invest. 2012 Jan;92(1):82-90. doi: 10.1038/labinvest.2011.131. Epub 2011 Sep 12. Lab Invest. 2012. PMID: 21912376 Free article.

6

Regulation of pancreatic cancer TRAIL resistance by protein O-GlcNAcylation.

Yang SZ, Xu F, Yuan K, Sun Y, Zhou T, Zhao X, McDonald JM, Chen Y. Yang SZ, et al. Among authors: yuan k. Lab Invest. 2020 May;100(5):777-785. doi: 10.1038/s41374-019-0365-z. Epub 2020 Jan 2. Lab Invest. 2020. PMID: 31896813 Free PMC article.

7

Serum response factor regulates bone formation via IGF-1 and Runx2 signals.

Chen J, Yuan K, Mao X, Miano JM, Wu H, Chen Y. Chen J, et al. Among authors: yuan k. J Bone Miner Res. 2012 Aug;27(8):1659-68. doi: 10.1002/jbmr.1607. J Bone Miner Res. 2012. PMID: 22434656 Free PMC article.

8

Tamoxifen enhances therapeutic effects of gemcitabine on cholangiocarcinoma tumorigenesis.

Jing G, Yuan K, Turk AN, Jhala NC, Arnoletti JP, Zhang K, McDonald JM, Chen Y. Jing G, et al. Among authors: yuan k. Lab Invest. 2011 Jun;91(6):896-904. doi: 10.1038/labinvest.2011.60. Epub 2011 Apr 4. Lab Invest. 2011. PMID: 21464824 Free article.

9

Vascular smooth muscle cell Smad4 gene is important for mouse vascular development.

Mao X, Debenedittis P, Sun Y, Chen J, Yuan K, Jiao K, Chen Y. Mao X, et al. Among authors: yuan k. Arterioscler Thromb Vasc Biol. 2012 Sep;32(9):2171-7. doi: 10.1161/ATVBAHA.112.253872. Epub 2012 Jul 5. Arterioscler Thromb Vasc Biol. 2012. PMID: 22772757 Free PMC article.

10

Activation of AKT by O-linked N-acetylglucosamine induces vascular calcification in diabetes mellitus.

Heath JM, Sun Y, Yuan K, Bradley WE, Litovsky S, Dell'Italia LJ, Chatham JC, Wu H, Chen Y. Heath JM, et al. Among authors: yuan k. Circ Res. 2014 Mar 28;114(7):1094-102. doi: 10.1161/CIRCRESAHA.114.302968. Epub 2014 Feb 13. Circ Res. 2014. PMID: 24526702 Free PMC article.

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