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Discovery of the Aryl-phospho-indole IDX899, a Highly Potent Anti-HIV Non-nucleoside Reverse Transcriptase Inhibitor.
Dousson C, Alexandre FR, Amador A, Bonaric S, Bot S, Caillet C, Convard T, da Costa D, Lioure MP, Roland A, Rosinovsky E, Maldonado S, Parsy C, Trochet C, Storer R, Stewart A, Wang J, Mayes BA, Musiu C, Poddesu B, Vargiu L, Liuzzi M, Moussa A, Jakubik J, Hubbard L, Seifer M, Standring D. Dousson C, et al. Among authors: jakubik j. J Med Chem. 2016 Mar 10;59(5):1891-8. doi: 10.1021/acs.jmedchem.5b01430. Epub 2016 Feb 3. J Med Chem. 2016. PMID: 26804933
Novel Intraprostatic Magnetic Resonance-Guided Implantation of Multidrug-Eluting Microdevice for Testing of Systemic Therapy Agents In Situ: Proof of Concept in Intermediate-Risk and High-Risk Prostate Cancer.
Stone BV, Dominas CA, Bhagavatula SK, Ahn SW, Tatarova Z, Jakubik J, Matthew D, Mossanen M, Furtado D, Tuncali K, Hirsch MS, Hata N, Tempany C, Jonas O, Kibel AS. Stone BV, et al. Among authors: jakubik j. J Urol. 2025 Feb;213(2):173-182. doi: 10.1097/JU.0000000000004269. Epub 2024 Sep 30. J Urol. 2025. PMID: 39348711 Clinical Trial.
Progress on the development of Class A GPCR-biased ligands.
Morales P, Scharf MM, Bermudez M, Egyed A, Franco R, Hansen OK, Jagerovic N, Jakubík J, Keserű GM, Kiss DJ, Kozielewicz P, Larsen O, Majellaro M, Mallo-Abreu A, Navarro G, Prieto-Díaz R, Rosenkilde MM, Sotelo E, Stark H, Werner T, Wingler LM. Morales P, et al. Among authors: jakubik j. Br J Pharmacol. 2024 Sep 11. doi: 10.1111/bph.17301. Online ahead of print. Br J Pharmacol. 2024. PMID: 39261899 Review.
Agonist-selective activation of individual G-proteins by muscarinic receptors.
Nelic D, Chetverikov N, Hochmalová M, Diaz C, Doležal V, Boulos J, Jakubík J, Martemyanov K, Janoušková-Randáková A. Nelic D, et al. Among authors: jakubik j. Sci Rep. 2024 Apr 26;14(1):9652. doi: 10.1038/s41598-024-60259-4. Sci Rep. 2024. PMID: 38671143 Free PMC article.
Muscarinic Receptors in Cardioprotection and Vascular Tone Regulation.
Dolejší E, Janoušková A, Jakubík J. Dolejší E, et al. Among authors: jakubik j. Physiol Res. 2024 Apr 18;73(Suppl 1):S389-S400. doi: 10.33549/physiolres.935270. Epub 2024 Apr 18. Physiol Res. 2024. PMID: 38634650 Free PMC article. Review.
Single-Shot ChAd3-MARV Vaccine in Modified Formulation Buffer Shows 100% Protection of NHPs.
Finch CL, King TH, Alfson KJ, Albanese KA, Smith JNP, Smock P, Jakubik J, Goez-Gazi Y, Gazi M, Dutton JW 3rd, Clemmons EA, Mattix ME, Carrion R Jr, Rudge T Jr, Ridenour A, Woodin SF, Hunegnaw R, Sullivan NJ, Xu R. Finch CL, et al. Among authors: jakubik j. Vaccines (Basel). 2022 Nov 15;10(11):1935. doi: 10.3390/vaccines10111935. Vaccines (Basel). 2022. PMID: 36423030 Free PMC article.
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