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Brain-Permeant and -Impermeant Inhibitors of Fatty Acid Amide Hydrolase Synergize with the Opioid Analgesic Morphine to Suppress Chemotherapy-Induced Neuropathic Nociception Without Enhancing Effects of Morphine on Gastrointestinal Transit.
Slivicki RA, Saberi SA, Iyer V, Vemuri VK, Makriyannis A, Hohmann AG. Slivicki RA, et al. Among authors: hohmann ag. J Pharmacol Exp Ther. 2018 Dec;367(3):551-563. doi: 10.1124/jpet.118.252288. Epub 2018 Oct 1. J Pharmacol Exp Ther. 2018. PMID: 30275151 Free PMC article.
Brain permeant and impermeant inhibitors of fatty-acid amide hydrolase suppress the development and maintenance of paclitaxel-induced neuropathic pain without producing tolerance or physical dependence in vivo and synergize with paclitaxel to reduce tumor cell line viability in vitro.
Slivicki RA, Xu Z, Mali SS, Hohmann AG. Slivicki RA, et al. Among authors: hohmann ag. Pharmacol Res. 2019 Apr;142:267-282. doi: 10.1016/j.phrs.2019.02.002. Epub 2019 Feb 7. Pharmacol Res. 2019. PMID: 30739035 Free PMC article.
Positive Allosteric Modulation of CB1 Cannabinoid Receptor Signaling Enhances Morphine Antinociception and Attenuates Morphine Tolerance Without Enhancing Morphine- Induced Dependence or Reward.
Slivicki RA, Iyer V, Mali SS, Garai S, Thakur GA, Crystal JD, Hohmann AG. Slivicki RA, et al. Among authors: hohmann ag. Front Mol Neurosci. 2020 Apr 28;13:54. doi: 10.3389/fnmol.2020.00054. eCollection 2020. Front Mol Neurosci. 2020. PMID: 32410959 Free PMC article.
131 results