Rye PD - Search Results

1

A New Class of Safe Oligosaccharide Polymer Therapy To Modify the Mucus Barrier of Chronic Respiratory Disease.

Pritchard MF, Powell LC, Menzies GE, Lewis PD, Hawkins K, Wright C, Doull I, Walsh TR, Onsøyen E, Dessen A, Myrvold R, Rye PD, Myrset AH, Stevens HN, Hodges LA, MacGregor G, Neilly JB, Hill KE, Thomas DW. Pritchard MF, et al. Among authors: rye pd. Mol Pharm. 2016 Mar 7;13(3):863-72. doi: 10.1021/acs.molpharmaceut.5b00794. Epub 2016 Feb 16. Mol Pharm. 2016. PMID: 26833139 Free article.

2

A nanoscale characterization of the interaction of a novel alginate oligomer with the cell surface and motility of Pseudomonas aeruginosa.

Powell LC, Pritchard MF, Emanuel C, Onsøyen E, Rye PD, Wright CJ, Hill KE, Thomas DW. Powell LC, et al. Among authors: rye pd. Am J Respir Cell Mol Biol. 2014 Mar;50(3):483-92. doi: 10.1165/rcmb.2013-0287OC. Am J Respir Cell Mol Biol. 2014. PMID: 24074505 Free article.

3

Alginate oligosaccharides inhibit fungal cell growth and potentiate the activity of antifungals against Candida and Aspergillus spp.

Tøndervik A, Sletta H, Klinkenberg G, Emanuel C, Powell LC, Pritchard MF, Khan S, Craine KM, Onsøyen E, Rye PD, Wright C, Thomas DW, Hill KE. Tøndervik A, et al. Among authors: rye pd. PLoS One. 2014 Nov 19;9(11):e112518. doi: 10.1371/journal.pone.0112518. eCollection 2014. PLoS One. 2014. PMID: 25409186 Free PMC article.

4

OligoG CF-5/20 Disruption of Mucoid Pseudomonas aeruginosa Biofilm in a Murine Lung Infection Model.

Hengzhuang W, Song Z, Ciofu O, Onsøyen E, Rye PD, Høiby N. Hengzhuang W, et al. Among authors: rye pd. Antimicrob Agents Chemother. 2016 Apr 22;60(5):2620-6. doi: 10.1128/AAC.01721-15. Print 2016 May. Antimicrob Agents Chemother. 2016. PMID: 26833153 Free PMC article.

5

A novel guluronate oligomer improves intestinal transit and survival in cystic fibrosis mice.

Vitko M, Valerio DM, Rye PD, Onsøyen E, Myrset AH, Dessen A, Drumm ML, Hodges CA. Vitko M, et al. Among authors: rye pd. J Cyst Fibros. 2016 Nov;15(6):745-751. doi: 10.1016/j.jcf.2016.06.005. Epub 2016 Jun 21. J Cyst Fibros. 2016. PMID: 27343003 Free article.

6

OligoG CF-5/20 normalizes cystic fibrosis mucus by chelating calcium.

Ermund A, Recktenwald CV, Skjåk-Braek G, Meiss LN, Onsøyen E, Rye PD, Dessen A, Myrset AH, Hansson GC. Ermund A, et al. Among authors: rye pd. Clin Exp Pharmacol Physiol. 2017 Jun;44(6):639-647. doi: 10.1111/1440-1681.12744. Clin Exp Pharmacol Physiol. 2017. PMID: 28261854

7

The antimicrobial effects of the alginate oligomer OligoG CF-5/20 are independent of direct bacterial cell membrane disruption.

Pritchard MF, Powell LC, Khan S, Griffiths PC, Mansour OT, Schweins R, Beck K, Buurma NJ, Dempsey CE, Wright CJ, Rye PD, Hill KE, Thomas DW, Ferguson EL. Pritchard MF, et al. Among authors: rye pd. Sci Rep. 2017 Mar 31;7:44731. doi: 10.1038/srep44731. Sci Rep. 2017. PMID: 28361894 Free PMC article.

8

A Low-Molecular-Weight Alginate Oligosaccharide Disrupts Pseudomonal Microcolony Formation and Enhances Antibiotic Effectiveness.

Pritchard MF, Powell LC, Jack AA, Powell K, Beck K, Florance H, Forton J, Rye PD, Dessen A, Hill KE, Thomas DW. Pritchard MF, et al. Among authors: rye pd. Antimicrob Agents Chemother. 2017 Aug 24;61(9):e00762-17. doi: 10.1128/AAC.00762-17. Print 2017 Sep. Antimicrob Agents Chemother. 2017. PMID: 28630204 Free PMC article.

9

Alginate oligosaccharides modify hyphal infiltration of Candida albicans in an in vitro model of invasive human candidosis.

Pritchard MF, Jack AA, Powell LC, Sadh H, Rye PD, Hill KE, Thomas DW. Pritchard MF, et al. Among authors: rye pd. J Appl Microbiol. 2017 Sep;123(3):625-636. doi: 10.1111/jam.13516. Epub 2017 Aug 1. J Appl Microbiol. 2017. PMID: 28635170

10

Alginate Oligosaccharide-Induced Modification of the lasI-lasR and rhlI-rhlR Quorum-Sensing Systems in Pseudomonas aeruginosa.

Jack AA, Khan S, Powell LC, Pritchard MF, Beck K, Sadh H, Sutton L, Cavaliere A, Florance H, Rye PD, Thomas DW, Hill KE. Jack AA, et al. Among authors: rye pd. Antimicrob Agents Chemother. 2018 Apr 26;62(5):e02318-17. doi: 10.1128/AAC.02318-17. Print 2018 May. Antimicrob Agents Chemother. 2018. PMID: 29463534 Free PMC article.

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