Vitcheva V - Search Results

1

The application of molecular modelling in the safety assessment of chemicals: A case study on ligand-dependent PPARγ dysregulation.

Al Sharif M, Tsakovska I, Pajeva I, Alov P, Fioravanzo E, Bassan A, Kovarich S, Yang C, Mostrag-Szlichtyng A, Vitcheva V, Worth AP, Richarz AN, Cronin MTD. Al Sharif M, et al. Among authors: vitcheva v. Toxicology. 2017 Dec 1;392:140-154. doi: 10.1016/j.tox.2016.01.009. Epub 2016 Feb 4. Toxicology. 2017. PMID: 26836498

2

Molecular determinants of PPARγ partial agonism and related in silico/in vivo studies of natural saponins as potential type 2 diabetes modulators.

Al Sharif M, Alov P, Diukendjieva A, Vitcheva V, Simeonova R, Krasteva I, Shkondrov A, Tsakovska I, Pajeva I. Al Sharif M, et al. Among authors: vitcheva v. Food Chem Toxicol. 2018 Feb;112:47-59. doi: 10.1016/j.fct.2017.12.009. Epub 2017 Dec 13. Food Chem Toxicol. 2018. PMID: 29247773

3

Molecular Modeling Approach to Study the PPARγ-Ligand Interactions.

Al Sharif M, Tsakovska I, Alov P, Vitcheva V, Diukendjieva A, Pajeva I. Al Sharif M, et al. Among authors: vitcheva v. Methods Mol Biol. 2019;1966:261-289. doi: 10.1007/978-1-4939-9195-2_22. Methods Mol Biol. 2019. PMID: 31041755

4

In silico and in vivo studies of Astragalus glycyphylloides saponin(s) with relevance to metabolic syndrome modulation.

Al Sharif M, Vitcheva V, Simeonova R, Krasteva I, Manov V, Alov P, Popov G, Shkondrov A, Pajeva I. Al Sharif M, et al. Among authors: vitcheva v. Food Chem Toxicol. 2019 Aug;130:317-325. doi: 10.1016/j.fct.2019.05.032. Epub 2019 May 23. Food Chem Toxicol. 2019. PMID: 31128217

5

Modes-of-Action Related to Repeated Dose Toxicity: Tissue-Specific Biological Roles of PPAR γ Ligand-Dependent Dysregulation in Nonalcoholic Fatty Liver Disease.

Al Sharif M, Alov P, Vitcheva V, Pajeva I, Tsakovska I. Al Sharif M, et al. Among authors: vitcheva v. PPAR Res. 2014;2014:432647. doi: 10.1155/2014/432647. Epub 2014 Mar 18. PPAR Res. 2014. PMID: 24772164 Free PMC article. Review.

6

Natural modulators of nonalcoholic fatty liver disease: Mode of action analysis and in silico ADME-Tox prediction.

Al Sharif M, Alov P, Vitcheva V, Diukendjieva A, Mori M, Botta B, Tsakovska I, Pajeva I. Al Sharif M, et al. Among authors: vitcheva v. Toxicol Appl Pharmacol. 2017 Dec 15;337:45-66. doi: 10.1016/j.taap.2017.10.013. Epub 2017 Nov 5. Toxicol Appl Pharmacol. 2017. PMID: 29056366

7

Thresholds of Toxicological Concern for cosmetics-related substances: New database, thresholds, and enrichment of chemical space.

Yang C, Barlow SM, Muldoon Jacobs KL, Vitcheva V, Boobis AR, Felter SP, Arvidson KB, Keller D, Cronin MTD, Enoch S, Worth A, Hollnagel HM. Yang C, et al. Among authors: vitcheva v. Food Chem Toxicol. 2017 Nov;109(Pt 1):170-193. doi: 10.1016/j.fct.2017.08.043. Epub 2017 Sep 1. Food Chem Toxicol. 2017. PMID: 28867342 Free article.

8

COSMOS next generation - A public knowledge base leveraging chemical and biological data to support the regulatory assessment of chemicals.

Yang C, Cronin MTD, Arvidson KB, Bienfait B, Enoch SJ, Heldreth B, Hobocienski B, Muldoon-Jacobs K, Lan Y, Madden JC, Magdziarz T, Marusczyk J, Mostrag A, Nelms M, Neagu D, Przybylak K, Rathman JF, Park J, Richarz AN, Richard AM, Ribeiro JV, Sacher O, Schwab C, Vitcheva V, Volarath P, Worth AP. Yang C, et al. Among authors: vitcheva v. Comput Toxicol. 2021 Aug;19:100175. doi: 10.1016/j.comtox.2021.100175. Comput Toxicol. 2021. PMID: 34405124 Free PMC article.

9

A new paradigm in threshold of toxicological concern based on chemoinformatics analysis of a highly curated database enriched with antimicrobials.

Yang C, Cheeseman M, Rathman J, Mostrag A, Skoulis N, Vitcheva V, Goldberg S. Yang C, et al. Among authors: vitcheva v. Food Chem Toxicol. 2020 Sep;143:111561. doi: 10.1016/j.fct.2020.111561. Epub 2020 Jul 5. Food Chem Toxicol. 2020. PMID: 32640338

10

Effect of cytisine on some brain and hepatic biochemical parameters in spontaneously hypertensive rats.

Simeonova R, Vitcheva V, Mitcheva M. Simeonova R, et al. Among authors: vitcheva v. Interdiscip Toxicol. 2010 Mar;3(1):21-5. doi: 10.2478/v10102-010-0004-4. Epub 2010 Mar 29. Interdiscip Toxicol. 2010. PMID: 21217867 Free PMC article.

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