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Assessment of the Worldwide Antimalarial Resistance Network Standardized Procedure for In Vitro Malaria Drug Sensitivity Testing Using SYBR Green Assay for Field Samples with Various Initial Parasitemia Levels.
Cheruiyot AC, Auschwitz JM, Lee PJ, Yeda RA, Okello CO, Leed SE, Talwar M, Murthy T, Gaona HW, Hickman MR, Akala HM, Kamau E, Johnson JD. Cheruiyot AC, et al. Among authors: hickman mr. Antimicrob Agents Chemother. 2016 Mar 25;60(4):2417-24. doi: 10.1128/AAC.00527-15. Print 2016 Apr. Antimicrob Agents Chemother. 2016. PMID: 26856829 Free PMC article.
Ketotifen is an antimalarial prodrug of norketotifen with blood schizonticidal and liver-stage efficacy.
Milner E, Sousa J, Pybus B, Auschwitz J, Caridha D, Gardner S, Grauer K, Harris E, Hickman M, Kozar MP, Lee P, Leed S, Li Q, Melendez V, Moon J, Ngundam F, O'Neil M, Parriott S, Potter B, Sciotti R, Tangteung A, Dow GS. Milner E, et al. Eur J Drug Metab Pharmacokinet. 2012 Mar;37(1):17-22. doi: 10.1007/s13318-012-0080-2. Eur J Drug Metab Pharmacokinet. 2012. PMID: 22314893
Novel N-benzoyl-2-hydroxybenzamide disrupts unique parasite secretory pathway.
Fomovska A, Huang Q, El Bissati K, Mui EJ, Witola WH, Cheng G, Zhou Y, Sommerville C, Roberts CW, Bettis S, Prigge ST, Afanador GA, Hickman MR, Lee PJ, Leed SE, Auschwitz JM, Pieroni M, Stec J, Muench SP, Rice DW, Kozikowski AP, McLeod R. Fomovska A, et al. Among authors: hickman mr. Antimicrob Agents Chemother. 2012 May;56(5):2666-82. doi: 10.1128/AAC.06450-11. Epub 2012 Feb 21. Antimicrob Agents Chemother. 2012. PMID: 22354304 Free PMC article.
Use of Optical Imaging Technology in the Validation of a New, Rapid, Cost-Effective Drug Screen as Part of a Tiered In Vivo Screening Paradigm for Development of Drugs To Treat Cutaneous Leishmaniasis.
Caridha D, Parriot S, Hudson TH, Lang T, Ngundam F, Leed S, Sena J, Harris M, O'Neil M, Sciotti R, Read L, Lecoeur H, Hickman M, Grogl M. Caridha D, et al. Antimicrob Agents Chemother. 2017 Mar 24;61(4):e02048-16. doi: 10.1128/AAC.02048-16. Print 2017 Apr. Antimicrob Agents Chemother. 2017. PMID: 28137819 Free PMC article.
Salicylanilide inhibitors of Toxoplasma gondii.
Fomovska A, Wood RD, Mui E, Dubey JP, Ferreira LR, Hickman MR, Lee PJ, Leed SE, Auschwitz JM, Welsh WJ, Sommerville C, Woods S, Roberts C, McLeod R. Fomovska A, et al. Among authors: hickman mr. J Med Chem. 2012 Oct 11;55(19):8375-91. doi: 10.1021/jm3007596. Epub 2012 Sep 26. J Med Chem. 2012. PMID: 22970937 Free PMC article.
From a cytotoxic agent to the discovery of a novel antimalarial agent.
Singh RS, Das U, Auschwitz JM, Leed SE, Hickman MR, Dimmock JR, Alcorn J. Singh RS, et al. Among authors: hickman mr. Bioorg Med Chem Lett. 2013 Jan 15;23(2):584-7. doi: 10.1016/j.bmcl.2012.10.126. Epub 2012 Nov 15. Bioorg Med Chem Lett. 2013. PMID: 23228469
Updating the modified Thompson test by using whole-body bioluminescence imaging to replace traditional efficacy testing in experimental models of murine malaria.
Caridha D, Hickman M, Xie L, Ngundam F, Milner E, Schenk A, Butler K, Nugent D, Lee P, Roncal N, Leed S, Hosford E, Lee J, Sciotti RJ, Reichard G, Black C, Kreishman-Deitrick M, Li Q, Vesely B. Caridha D, et al. Malar J. 2019 Feb 15;18(1):38. doi: 10.1186/s12936-019-2661-x. Malar J. 2019. PMID: 30767768 Free PMC article.
41 results