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Page 1
Effective treatment of steatosis and steatohepatitis by fibroblast growth factor 1 in mouse models of nonalcoholic fatty liver disease.
Liu W, Struik D, Nies VJ, Jurdzinski A, Harkema L, de Bruin A, Verkade HJ, Downes M, Evans RM, van Zutphen T, Jonker JW. Liu W, et al. Among authors: de bruin a. Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2288-93. doi: 10.1073/pnas.1525093113. Epub 2016 Feb 8. Proc Natl Acad Sci U S A. 2016. PMID: 26858440 Free PMC article.
Tumor necrosis factor receptor 1 gain-of-function mutation aggravates nonalcoholic fatty liver disease but does not cause insulin resistance in a murine model.
Aparicio-Vergara M, Hommelberg PP, Schreurs M, Gruben N, Stienstra R, Shiri-Sverdlov R, Kloosterhuis NJ, de Bruin A, van de Sluis B, Koonen DP, Hofker MH. Aparicio-Vergara M, et al. Among authors: de bruin a. Hepatology. 2013 Feb;57(2):566-76. doi: 10.1002/hep.26046. Epub 2013 Jan 10. Hepatology. 2013. PMID: 22941955
Increased hepatic CD36 expression with age is associated with enhanced susceptibility to nonalcoholic fatty liver disease.
Sheedfar F, Sung MM, Aparicio-Vergara M, Kloosterhuis NJ, Miquilena-Colina ME, Vargas-Castrillón J, Febbraio M, Jacobs RL, de Bruin A, Vinciguerra M, García-Monzón C, Hofker MH, Dyck JR, Koonen DP. Sheedfar F, et al. Among authors: de bruin a. Aging (Albany NY). 2014 Apr;6(4):281-95. doi: 10.18632/aging.100652. Aging (Albany NY). 2014. PMID: 24751397 Free PMC article.
Chemokine-like receptor 1 deficiency does not affect the development of insulin resistance and nonalcoholic fatty liver disease in mice.
Gruben N, Aparicio Vergara M, Kloosterhuis NJ, van der Molen H, Stoelwinder S, Youssef S, de Bruin A, Delsing DJ, Kuivenhoven JA, van de Sluis B, Hofker MH, Koonen DP. Gruben N, et al. Among authors: de bruin a. PLoS One. 2014 Apr 29;9(4):e96345. doi: 10.1371/journal.pone.0096345. eCollection 2014. PLoS One. 2014. PMID: 24781986 Free PMC article.
Pathology of Mouse Models of Accelerated Aging.
Harkema L, Youssef SA, de Bruin A. Harkema L, et al. Among authors: de bruin a. Vet Pathol. 2016 Mar;53(2):366-89. doi: 10.1177/0300985815625169. Epub 2016 Feb 10. Vet Pathol. 2016. PMID: 26864891 Review.
Full ablation of C9orf72 in mice causes immune system-related pathology and neoplastic events but no motor neuron defects.
Sudria-Lopez E, Koppers M, de Wit M, van der Meer C, Westeneng HJ, Zundel CA, Youssef SA, Harkema L, de Bruin A, Veldink JH, van den Berg LH, Pasterkamp RJ. Sudria-Lopez E, et al. Among authors: de wit m, de bruin a. Acta Neuropathol. 2016 Jul;132(1):145-7. doi: 10.1007/s00401-016-1581-x. Epub 2016 May 20. Acta Neuropathol. 2016. PMID: 27206760 Free PMC article. No abstract available.
NF-κB p65 serine 467 phosphorylation sensitizes mice to weight gain and TNFα-or diet-induced inflammation.
Riedlinger T, Dommerholt MB, Wijshake T, Kruit JK, Huijkman N, Dekker D, Koster M, Kloosterhuis N, Koonen DPY, de Bruin A, Baker D, Hofker MH, van Deursen J, Jonker JW, Schmitz ML, van de Sluis B. Riedlinger T, et al. Among authors: de bruin a. Biochim Biophys Acta Mol Cell Res. 2017 Oct;1864(10):1785-1798. doi: 10.1016/j.bbamcr.2017.07.005. Epub 2017 Jul 16. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 28723419 Free article.
Reduced expression of C/EBPβ-LIP extends health and lifespan in mice.
Müller C, Zidek LM, Ackermann T, de Jong T, Liu P, Kliche V, Zaini MA, Kortman G, Harkema L, Verbeek DS, Tuckermann JP, von Maltzahn J, de Bruin A, Guryev V, Wang ZQ, Calkhoven CF. Müller C, et al. Among authors: de jong t, de bruin a. Elife. 2018 Jun 4;7:e34985. doi: 10.7554/eLife.34985. Elife. 2018. PMID: 29708496 Free PMC article.
LED-phototherapy does not induce oxidative DNA damage in hyperbilirubinemic Gunn rats.
van der Schoor LWE, Hulzebos CV, van Faassen MH, Kema IP, de Bruin A, Havinga R, Koster M, Youssef SA, Bongiovanni L, Jonker JW, Verkade HJ. van der Schoor LWE, et al. Among authors: de bruin a. Pediatr Res. 2019 Jun;85(7):1041-1047. doi: 10.1038/s41390-019-0367-y. Epub 2019 Mar 9. Pediatr Res. 2019. PMID: 30851724
392 results