Jin J - Search Results

1

Characterization of Behavioral, Neuropathological, Brain Metabolic and Key Molecular Changes in zQ175 Knock-In Mouse Model of Huntington's Disease.

Peng Q, Wu B, Jiang M, Jin J, Hou Z, Zheng J, Zhang J, Duan W. Peng Q, et al. Among authors: jin j. PLoS One. 2016 Feb 9;11(2):e0148839. doi: 10.1371/journal.pone.0148839. eCollection 2016. PLoS One. 2016. PMID: 26859386 Free PMC article.

2

trans-(-)-ε-Viniferin increases mitochondrial sirtuin 3 (SIRT3), activates AMP-activated protein kinase (AMPK), and protects cells in models of Huntington Disease.

Fu J, Jin J, Cichewicz RH, Hageman SA, Ellis TK, Xiang L, Peng Q, Jiang M, Arbez N, Hotaling K, Ross CA, Duan W. Fu J, et al. Among authors: jin j. J Biol Chem. 2012 Jul 13;287(29):24460-72. doi: 10.1074/jbc.M112.382226. Epub 2012 May 30. J Biol Chem. 2012. PMID: 22648412 Free PMC article.

3

Interrogation of brain miRNA and mRNA expression profiles reveals a molecular regulatory network that is perturbed by mutant huntingtin.

Jin J, Cheng Y, Zhang Y, Wood W, Peng Q, Hutchison E, Mattson MP, Becker KG, Duan W. Jin J, et al. J Neurochem. 2012 Nov;123(4):477-90. doi: 10.1111/j.1471-4159.2012.07925.x. Epub 2012 Sep 28. J Neurochem. 2012. PMID: 22906125 Free PMC article.

4

Neuroprotective effects of PPAR-γ agonist rosiglitazone in N171-82Q mouse model of Huntington's disease.

Jin J, Albertz J, Guo Z, Peng Q, Rudow G, Troncoso JC, Ross CA, Duan W. Jin J, et al. J Neurochem. 2013 May;125(3):410-9. doi: 10.1111/jnc.12190. Epub 2013 Mar 5. J Neurochem. 2013. PMID: 23373812 Free PMC article.

5

Small-molecule TrkB receptor agonists improve motor function and extend survival in a mouse model of Huntington's disease.

Jiang M, Peng Q, Liu X, Jin J, Hou Z, Zhang J, Mori S, Ross CA, Ye K, Duan W. Jiang M, et al. Among authors: jin j. Hum Mol Genet. 2013 Jun 15;22(12):2462-70. doi: 10.1093/hmg/ddt098. Epub 2013 Feb 27. Hum Mol Genet. 2013. PMID: 23446639 Free PMC article.

6

Metabolism in HD: still a relevant mechanism?

Duan W, Jiang M, Jin J. Duan W, et al. Among authors: jin j. Mov Disord. 2014 Sep 15;29(11):1366-74. doi: 10.1002/mds.25992. Epub 2014 Aug 13. Mov Disord. 2014. PMID: 25124273 Free PMC article. Review.

7

Early white matter abnormalities, progressive brain pathology and motor deficits in a novel knock-in mouse model of Huntington's disease.

Jin J, Peng Q, Hou Z, Jiang M, Wang X, Langseth AJ, Tao M, Barker PB, Mori S, Bergles DE, Ross CA, Detloff PJ, Zhang J, Duan W. Jin J, et al. Hum Mol Genet. 2015 May 1;24(9):2508-27. doi: 10.1093/hmg/ddv016. Epub 2015 Jan 21. Hum Mol Genet. 2015. PMID: 25609071 Free PMC article.

8

Metformin Protects Cells from Mutant Huntingtin Toxicity Through Activation of AMPK and Modulation of Mitochondrial Dynamics.

Jin J, Gu H, Anders NM, Ren T, Jiang M, Tao M, Peng Q, Rudek MA, Duan W. Jin J, et al. Neuromolecular Med. 2016 Dec;18(4):581-592. doi: 10.1007/s12017-016-8412-z. Epub 2016 May 25. Neuromolecular Med. 2016. PMID: 27225841 Free PMC article.

9

Huntingtin silencing delays onset and slows progression of Huntington's disease: a biomarker study.

Liu H, Zhang C, Xu J, Jin J, Cheng L, Miao X, Wu Q, Wei Z, Liu P, Lu H, van Zijl PCM, Ross CA, Hua J, Duan W. Liu H, et al. Among authors: jin j. Brain. 2021 Nov 29;144(10):3101-3113. doi: 10.1093/brain/awab190. Brain. 2021. PMID: 34043007 Free PMC article.

10

Interaction of huntingtin with PRMTs and its subsequent arginine methylation affects HTT solubility, phase transition behavior and neuronal toxicity.

Ratovitski T, Jiang M, O'Meally RN, Rauniyar P, Chighladze E, Faragó A, Kamath SV, Jin J, Shevelkin AV, Cole RN, Ross CA. Ratovitski T, et al. Among authors: jin j. Hum Mol Genet. 2022 May 19;31(10):1651-1672. doi: 10.1093/hmg/ddab351. Hum Mol Genet. 2022. PMID: 34888656 Free PMC article.

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