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Page 1
Increased Secondary Nucleation Underlies Accelerated Aggregation of the Four-Residue N-Terminally Truncated Aβ42 Species Aβ5-42.
Weiffert T, Meisl G, Flagmeier P, De S, Dunning CJR, Frohm B, Zetterberg H, Blennow K, Portelius E, Klenerman D, Dobson CM, Knowles TPJ, Linse S. Weiffert T, et al. Among authors: dunning cjr. ACS Chem Neurosci. 2019 May 15;10(5):2374-2384. doi: 10.1021/acschemneuro.8b00676. Epub 2019 Mar 8. ACS Chem Neurosci. 2019. PMID: 30793584
A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers.
Cohen SIA, Arosio P, Presto J, Kurudenkandy FR, Biverstal H, Dolfe L, Dunning C, Yang X, Frohm B, Vendruscolo M, Johansson J, Dobson CM, Fisahn A, Knowles TPJ, Linse S. Cohen SIA, et al. Nat Struct Mol Biol. 2015 Mar;22(3):207-213. doi: 10.1038/nsmb.2971. Epub 2015 Feb 16. Nat Struct Mol Biol. 2015. PMID: 25686087 Free PMC article.
Acceleration of α-synuclein aggregation by exosomes.
Grey M, Dunning CJ, Gaspar R, Grey C, Brundin P, Sparr E, Linse S. Grey M, et al. Among authors: dunning cj. J Biol Chem. 2015 Jan 30;290(5):2969-82. doi: 10.1074/jbc.M114.585703. Epub 2014 Nov 25. J Biol Chem. 2015. PMID: 25425650 Free PMC article.