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Inflammasome-dependent IL-1β release depends upon membrane permeabilisation.
Martín-Sánchez F, Diamond C, Zeitler M, Gomez AI, Baroja-Mazo A, Bagnall J, Spiller D, White M, Daniels MJ, Mortellaro A, Peñalver M, Paszek P, Steringer JP, Nickel W, Brough D, Pelegrín P. Martín-Sánchez F, et al. Among authors: daniels mj. Cell Death Differ. 2016 Jul;23(7):1219-31. doi: 10.1038/cdd.2015.176. Epub 2016 Feb 12. Cell Death Differ. 2016. PMID: 26868913 Free PMC article.
Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models.
Daniels MJ, Rivers-Auty J, Schilling T, Spencer NG, Watremez W, Fasolino V, Booth SJ, White CS, Baldwin AG, Freeman S, Wong R, Latta C, Yu S, Jackson J, Fischer N, Koziel V, Pillot T, Bagnall J, Allan SM, Paszek P, Galea J, Harte MK, Eder C, Lawrence CB, Brough D. Daniels MJ, et al. Nat Commun. 2016 Aug 11;7:12504. doi: 10.1038/ncomms12504. Nat Commun. 2016. PMID: 27509875 Free PMC article.
P2X7 receptor-dependent tuning of gut epithelial responses to infection.
Huang SW, Walker C, Pennock J, Else K, Muller W, Daniels MJ, Pellegrini C, Brough D, Lopez-Castejon G, Cruickshank SM. Huang SW, et al. Among authors: daniels mj. Immunol Cell Biol. 2017 Feb;95(2):178-188. doi: 10.1038/icb.2016.75. Epub 2016 Aug 25. Immunol Cell Biol. 2017. PMID: 27559003 Free PMC article.
Boron-Based Inhibitors of the NLRP3 Inflammasome.
Baldwin AG, Rivers-Auty J, Daniels MJD, White CS, Schwalbe CH, Schilling T, Hammadi H, Jaiyong P, Spencer NG, England H, Luheshi NM, Kadirvel M, Lawrence CB, Rothwell NJ, Harte MK, Bryce RA, Allan SM, Eder C, Freeman S, Brough D. Baldwin AG, et al. Cell Chem Biol. 2017 Nov 16;24(11):1321-1335.e5. doi: 10.1016/j.chembiol.2017.08.011. Epub 2017 Sep 21. Cell Chem Biol. 2017. PMID: 28943355 Free PMC article.
Zinc Status Alters Alzheimer's Disease Progression through NLRP3-Dependent Inflammation.
Rivers-Auty J, Tapia VS, White CS, Daniels MJD, Drinkall S, Kennedy PT, Spence HG, Yu S, Green JP, Hoyle C, Cook J, Bradley A, Mather AE, Peters R, Tzeng TC, Gordon MJ, Beattie JH, Brough D, Lawrence CB. Rivers-Auty J, et al. Among authors: daniels mjd. J Neurosci. 2021 Mar 31;41(13):3025-3038. doi: 10.1523/JNEUROSCI.1980-20.2020. Epub 2021 Feb 17. J Neurosci. 2021. PMID: 33597269 Free PMC article.
Deep proteomic analysis of microglia reveals fundamental biological differences between model systems.
Lloyd AF, Martinez-Muriana A, Davis E, Daniels MJD, Hou P, Mancuso R, Brenes AJ, Sinclair LV, Geric I, Snellinx A, Craessaerts K, Theys T, Fiers M, De Strooper B, Howden AJM. Lloyd AF, et al. Among authors: daniels mjd. Cell Rep. 2024 Nov 26;43(11):114908. doi: 10.1016/j.celrep.2024.114908. Epub 2024 Oct 25. Cell Rep. 2024. PMID: 39460937 Free article.
364 results