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Sprouty proteins are negative regulators of interferon (IFN) signaling and IFN-inducible biological responses.
Sharma B, Joshi S, Sassano A, Majchrzak B, Kaur S, Aggarwal P, Nabet B, Bulic M, Stein BL, McMahon B, Baker DP, Fukunaga R, Altman JK, Licht JD, Fish EN, Platanias LC. Sharma B, et al. Among authors: platanias lc. J Biol Chem. 2012 Dec 7;287(50):42352-60. doi: 10.1074/jbc.M112.400721. Epub 2012 Oct 16. J Biol Chem. 2012. PMID: 23074222 Free PMC article.
Essential role for the Mnk pathway in the inhibitory effects of type I interferons on myeloproliferative neoplasm (MPN) precursors.
Mehrotra S, Sharma B, Joshi S, Kroczynska B, Majchrzak B, Stein BL, McMahon B, Altman JK, Licht JD, Baker DP, Eklund EA, Wickrema A, Verma A, Fish EN, Platanias LC. Mehrotra S, et al. Among authors: platanias lc. J Biol Chem. 2013 Aug 16;288(33):23814-22. doi: 10.1074/jbc.M113.476192. Epub 2013 Jun 28. J Biol Chem. 2013. PMID: 23814052 Free PMC article.
Critical roles for Rictor/Sin1 complexes in interferon-dependent gene transcription and generation of antiproliferative responses.
Kaur S, Kroczynska B, Sharma B, Sassano A, Arslan AD, Majchrzak-Kita B, Stein BL, McMahon B, Altman JK, Su B, Calogero RA, Fish EN, Platanias LC. Kaur S, et al. Among authors: platanias lc. J Biol Chem. 2014 Mar 7;289(10):6581-6591. doi: 10.1074/jbc.M113.537852. Epub 2014 Jan 27. J Biol Chem. 2014. PMID: 24469448 Free PMC article.
Use of mTOR inhibitors in the treatment of malignancies.
Mohindra NA, Giles FJ, Platanias LC. Mohindra NA, et al. Among authors: platanias lc. Expert Opin Pharmacother. 2014 May;15(7):979-90. doi: 10.1517/14656566.2014.899582. Epub 2014 Mar 25. Expert Opin Pharmacother. 2014. PMID: 24666371 Review.
Regulatory effects of SKAR in interferon α signaling and its role in the generation of type I IFN responses.
Kroczynska B, Mehrotra S, Majchrzak-Kita B, Arslan AD, Altman JK, Stein BL, McMahon B, Kozlowski P, Kahle PJ, Eklund EA, Fish EN, Platanias LC. Kroczynska B, et al. Among authors: platanias lc. Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11377-82. doi: 10.1073/pnas.1405250111. Epub 2014 Jul 21. Proc Natl Acad Sci U S A. 2014. PMID: 25049393 Free PMC article.
Targeting novel signaling pathways for resistant acute myeloid leukemia.
Sakamoto KM, Grant S, Saleiro D, Crispino JD, Hijiya N, Giles F, Platanias L, Eklund EA. Sakamoto KM, et al. Mol Genet Metab. 2015 Mar;114(3):397-402. doi: 10.1016/j.ymgme.2014.11.017. Epub 2014 Dec 5. Mol Genet Metab. 2015. PMID: 25533111 Free PMC article. Review.
380 results