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RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance.
Somasagara RR, Spencer SM, Tripathi K, Clark DW, Mani C, Madeira da Silva L, Scalici J, Kothayer H, Westwell AD, Rocconi RP, Palle K. Somasagara RR, et al. Among authors: clark dw. Oncogene. 2017 Nov 30;36(48):6680-6690. doi: 10.1038/onc.2017.279. Epub 2017 Aug 14. Oncogene. 2017. PMID: 28806395 Free PMC article.
RAD6 promotes chemoresistance in ovarian cancer.
Clark DW, Mani C, Palle K. Clark DW, et al. Mol Cell Oncol. 2017 Dec 18;5(1):e1392403. doi: 10.1080/23723556.2017.1392403. eCollection 2018. Mol Cell Oncol. 2017. PMID: 29404391 Free PMC article.
An oxidative DNA "damage" and repair mechanism localized in the VEGF promoter is important for hypoxia-induced VEGF mRNA expression.
Pastukh V, Roberts JT, Clark DW, Bardwell GC, Patel M, Al-Mehdi AB, Borchert GM, Gillespie MN. Pastukh V, et al. Among authors: clark dw. Am J Physiol Lung Cell Mol Physiol. 2015 Dec 1;309(11):L1367-75. doi: 10.1152/ajplung.00236.2015. Epub 2015 Oct 2. Am J Physiol Lung Cell Mol Physiol. 2015. PMID: 26432868 Free PMC article.
148 results