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Page 1
Torsins Are Essential Regulators of Cellular Lipid Metabolism.
Grillet M, Dominguez Gonzalez B, Sicart A, Pöttler M, Cascalho A, Billion K, Hernandez Diaz S, Swerts J, Naismith TV, Gounko NV, Verstreken P, Hanson PI, Goodchild RE. Grillet M, et al. Among authors: sicart a. Dev Cell. 2016 Aug 8;38(3):235-47. doi: 10.1016/j.devcel.2016.06.017. Epub 2016 Jul 21. Dev Cell. 2016. PMID: 27453503 Free article.
Differentiation but not ALS mutations in FUS rewires motor neuron metabolism.
Vandoorne T, Veys K, Guo W, Sicart A, Vints K, Swijsen A, Moisse M, Eelen G, Gounko NV, Fumagalli L, Fazal R, Germeys C, Quaegebeur A, Fendt SM, Carmeliet P, Verfaillie C, Van Damme P, Ghesquière B, De Bock K, Van Den Bosch L. Vandoorne T, et al. Among authors: sicart a. Nat Commun. 2019 Sep 12;10(1):4147. doi: 10.1038/s41467-019-12099-4. Nat Commun. 2019. PMID: 31515480 Free PMC article.
Targeting EGLN2/PHD1 protects motor neurons and normalizes the astrocytic interferon response.
Germeys C, Vandoorne T, Davie K, Poovathingal S, Heeren K, Vermeire W, Nami F, Moisse M, Quaegebeur A, Sierksma A, Rué L, Sicart A, Eykens C, De Cock L, De Strooper B, Carmeliet P, Van Damme P, De Bock K, Van Den Bosch L. Germeys C, et al. Among authors: sicart a. Cell Rep. 2024 Sep 24;43(9):114719. doi: 10.1016/j.celrep.2024.114719. Epub 2024 Sep 9. Cell Rep. 2024. PMID: 39255062 Free article.
PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport.
Tziortzouda P, Steyaert J, Scheveneels W, Sicart A, Stoklund Dittlau K, Barbosa Correia AM, Burg T, Pal A, Hermann A, Van Damme P, Moens TG, Van Den Bosch L. Tziortzouda P, et al. Among authors: sicart a. Acta Neuropathol. 2024 Feb 16;147(1):41. doi: 10.1007/s00401-024-02689-y. Acta Neuropathol. 2024. PMID: 38363426 Free PMC article.