Du Z - Search Results

1

Transcription-associated processes cause DNA double-strand breaks and translocations in neural stem/progenitor cells.

Schwer B, Wei PC, Chang AN, Kao J, Du Z, Meyers RM, Alt FW. Schwer B, et al. Among authors: du z. Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2258-63. doi: 10.1073/pnas.1525564113. Epub 2016 Feb 12. Proc Natl Acad Sci U S A. 2016. PMID: 26873106 Free PMC article.

2

Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching.

Dong J, Panchakshari RA, Zhang T, Zhang Y, Hu J, Volpi SA, Meyers RM, Ho YJ, Du Z, Robbiani DF, Meng F, Gostissa M, Nussenzweig MC, Manis JP, Alt FW. Dong J, et al. Among authors: du z. Nature. 2015 Sep 3;525(7567):134-139. doi: 10.1038/nature14970. Epub 2015 Aug 26. Nature. 2015. PMID: 26308889 Free PMC article.

3

Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells.

Wei PC, Chang AN, Kao J, Du Z, Meyers RM, Alt FW, Schwer B. Wei PC, et al. Among authors: du z. Cell. 2016 Feb 11;164(4):644-55. doi: 10.1016/j.cell.2015.12.039. Cell. 2016. PMID: 26871630 Free PMC article.

4

Highly sensitive and unbiased approach for elucidating antibody repertoires.

Lin SG, Ba Z, Du Z, Zhang Y, Hu J, Alt FW. Lin SG, et al. Among authors: du z. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7846-51. doi: 10.1073/pnas.1608649113. Epub 2016 Jun 27. Proc Natl Acad Sci U S A. 2016. PMID: 27354528 Free PMC article.

5

Sequence intrinsic somatic mutation mechanisms contribute to affinity maturation of VRC01-class HIV-1 broadly neutralizing antibodies.

Hwang JK, Wang C, Du Z, Meyers RM, Kepler TB, Neuberg D, Kwong PD, Mascola JR, Joyce MG, Bonsignori M, Haynes BF, Yeap LS, Alt FW. Hwang JK, et al. Among authors: du z. Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):8614-8619. doi: 10.1073/pnas.1709203114. Epub 2017 Jul 26. Proc Natl Acad Sci U S A. 2017. PMID: 28747530 Free PMC article.

6

DNA double-strand break response factors influence end-joining features of IgH class switch and general translocation junctions.

Panchakshari RA, Zhang X, Kumar V, Du Z, Wei PC, Kao J, Dong J, Alt FW. Panchakshari RA, et al. Among authors: du z. Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):762-767. doi: 10.1073/pnas.1719988115. Epub 2018 Jan 8. Proc Natl Acad Sci U S A. 2018. PMID: 29311308 Free PMC article.

7

Three classes of recurrent DNA break clusters in brain progenitors identified by 3D proximity-based break joining assay.

Wei PC, Lee CS, Du Z, Schwer B, Zhang Y, Kao J, Zurita J, Alt FW. Wei PC, et al. Among authors: du z. Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1919-1924. doi: 10.1073/pnas.1719907115. Epub 2018 Feb 5. Proc Natl Acad Sci U S A. 2018. PMID: 29432181 Free PMC article.

8

Convergent transcription at intragenic super-enhancers targets AID-initiated genomic instability.

Meng FL, Du Z, Federation A, Hu J, Wang Q, Kieffer-Kwon KR, Meyers RM, Amor C, Wasserman CR, Neuberg D, Casellas R, Nussenzweig MC, Bradner JE, Liu XS, Alt FW. Meng FL, et al. Among authors: du z. Cell. 2014 Dec 18;159(7):1538-48. doi: 10.1016/j.cell.2014.11.014. Epub 2014 Dec 4. Cell. 2014. PMID: 25483776 Free PMC article.

9

Chromosomal Loop Domains Direct the Recombination of Antigen Receptor Genes.

Hu J, Zhang Y, Zhao L, Frock RL, Du Z, Meyers RM, Meng FL, Schatz DG, Alt FW. Hu J, et al. Among authors: du z. Cell. 2015 Nov 5;163(4):947-59. doi: 10.1016/j.cell.2015.10.016. Epub 2015 Oct 22. Cell. 2015. PMID: 26593423 Free PMC article.

10

Orientation-specific RAG activity in chromosomal loop domains contributes to Tcrd V(D)J recombination during T cell development.

Zhao L, Frock RL, Du Z, Hu J, Chen L, Krangel MS, Alt FW. Zhao L, et al. Among authors: du z. J Exp Med. 2016 Aug 22;213(9):1921-36. doi: 10.1084/jem.20160670. Epub 2016 Aug 15. J Exp Med. 2016. PMID: 27526713 Free PMC article.

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