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Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons.
Krishnaswami SR, Grindberg RV, Novotny M, Venepally P, Lacar B, Bhutani K, Linker SB, Pham S, Erwin JA, Miller JA, Hodge R, McCarthy JK, Kelder M, McCorrison J, Aevermann BD, Fuertes FD, Scheuermann RH, Lee J, Lein ES, Schork N, McConnell MJ, Gage FH, Lasken RS. Krishnaswami SR, et al. Among authors: schork n. Nat Protoc. 2016 Mar;11(3):499-524. doi: 10.1038/nprot.2016.015. Epub 2016 Feb 18. Nat Protoc. 2016. PMID: 26890679 Free PMC article.
PRODUCTION OF A PRELIMINARY QUALITY CONTROL PIPELINE FOR SINGLE NUCLEI RNA-SEQ AND ITS APPLICATION IN THE ANALYSIS OF CELL TYPE DIVERSITY OF POST-MORTEM HUMAN BRAIN NEOCORTEX.
Aevermann B, McCorrison J, Venepally P, Hodge R, Bakken T, Miller J, Novotny M, Tran DN, Diezfuertes F, Christiansen L, Zhang F, Steemers F, Lasken RS, Lein ED, Schork N, Scheuermann RH. Aevermann B, et al. Among authors: schork n. Pac Symp Biocomput. 2017;22:564-575. doi: 10.1142/9789813207813_0052. Pac Symp Biocomput. 2017. PMID: 27897007 Free PMC article.
Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease.
Bryois J, Skene NG, Hansen TF, Kogelman LJA, Watson HJ, Liu Z; Eating Disorders Working Group of the Psychiatric Genomics Consortium; International Headache Genetics Consortium; 23andMe Research Team; Brueggeman L, Breen G, Bulik CM, Arenas E, Hjerling-Leffler J, Sullivan PF. Bryois J, et al. Nat Genet. 2020 May;52(5):482-493. doi: 10.1038/s41588-020-0610-9. Epub 2020 Apr 27. Nat Genet. 2020. PMID: 32341526 Free PMC article.
Understanding and predicting suicidality using a combined genomic and clinical risk assessment approach.
Niculescu AB, Levey DF, Phalen PL, Le-Niculescu H, Dainton HD, Jain N, Belanger E, James A, George S, Weber H, Graham DL, Schweitzer R, Ladd TB, Learman R, Niculescu EM, Vanipenta NP, Khan FN, Mullen J, Shankar G, Cook S, Humbert C, Ballew A, Yard M, Gelbart T, Shekhar A, Schork NJ, Kurian SM, Sandusky GE, Salomon DR. Niculescu AB, et al. Among authors: schork nj. Mol Psychiatry. 2015 Nov;20(11):1266-85. doi: 10.1038/mp.2015.112. Epub 2015 Aug 18. Mol Psychiatry. 2015. PMID: 26283638 Free PMC article.
Soluble α-synuclein-antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia.
Trudler D, Nazor KL, Eisele YS, Grabauskas T, Dolatabadi N, Parker J, Sultan A, Zhong Z, Goodwin MS, Levites Y, Golde TE, Kelly JW, Sierks MR, Schork NJ, Karin M, Ambasudhan R, Lipton SA. Trudler D, et al. Among authors: schork nj. Proc Natl Acad Sci U S A. 2021 Apr 13;118(15):e2025847118. doi: 10.1073/pnas.2025847118. Proc Natl Acad Sci U S A. 2021. PMID: 33833060 Free PMC article.
The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls.
Coleman JRI, Gaspar HA, Bryois J; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Breen G. Coleman JRI, et al. Biol Psychiatry. 2020 Jul 15;88(2):169-184. doi: 10.1016/j.biopsych.2019.10.015. Epub 2019 Nov 1. Biol Psychiatry. 2020. PMID: 31926635 Free PMC article.
623 results