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Skeletal muscle uncoupling-induced longevity in mice is linked to increased substrate metabolism and induction of the endogenous antioxidant defense system.
Keipert S, Ost M, Chadt A, Voigt A, Ayala V, Portero-Otin M, Pamplona R, Al-Hasani H, Klaus S. Keipert S, et al. Among authors: klaus s. Am J Physiol Endocrinol Metab. 2013 Mar 1;304(5):E495-506. doi: 10.1152/ajpendo.00518.2012. Epub 2012 Dec 31. Am J Physiol Endocrinol Metab. 2013. PMID: 23277187 Free article.
Muscle mitohormesis promotes cellular survival via serine/glycine pathway flux.
Ost M, Keipert S, van Schothorst EM, Donner V, van der Stelt I, Kipp AP, Petzke KJ, Jove M, Pamplona R, Portero-Otin M, Keijer J, Klaus S. Ost M, et al. Among authors: klaus s. FASEB J. 2015 Apr;29(4):1314-28. doi: 10.1096/fj.14-261503. Epub 2014 Dec 9. FASEB J. 2015. PMID: 25491309
Muscle mitochondrial stress adaptation operates independently of endogenous FGF21 action.
Ost M, Coleman V, Voigt A, van Schothorst EM, Keipert S, van der Stelt I, Ringel S, Graja A, Ambrosi T, Kipp AP, Jastroch M, Schulz TJ, Keijer J, Klaus S. Ost M, et al. Among authors: klaus s. Mol Metab. 2015 Nov 24;5(2):79-90. doi: 10.1016/j.molmet.2015.11.002. eCollection 2016 Feb. Mol Metab. 2015. PMID: 26909316 Free PMC article.
481 results