Blackwell HE - Search Results

1

Chemical Genetics Reveals Environment-Specific Roles for Quorum Sensing Circuits in Pseudomonas aeruginosa.

Welsh MA, Blackwell HE. Welsh MA, et al. Among authors: blackwell he. Cell Chem Biol. 2016 Mar 17;23(3):361-9. doi: 10.1016/j.chembiol.2016.01.006. Epub 2016 Feb 18. Cell Chem Biol. 2016. PMID: 26905657 Free PMC article.

2

Small molecule inhibitors of bacterial quorum sensing and biofilm formation.

Geske GD, Wezeman RJ, Siegel AP, Blackwell HE. Geske GD, et al. Among authors: blackwell he. J Am Chem Soc. 2005 Sep 21;127(37):12762-3. doi: 10.1021/ja0530321. J Am Chem Soc. 2005. PMID: 16159245

3

Interception of quorum sensing in Staphylococcus aureus: a new niche for peptidomimetics.

Gorske BC, Blackwell HE. Gorske BC, et al. Among authors: blackwell he. Org Biomol Chem. 2006 Apr 21;4(8):1441-5. doi: 10.1039/b517681f. Epub 2006 Mar 16. Org Biomol Chem. 2006. PMID: 16604206 Review.

4

Modulation of bacterial quorum sensing with synthetic ligands: systematic evaluation of N-acylated homoserine lactones in multiple species and new insights into their mechanisms of action.

Geske GD, O'Neill JC, Miller DM, Mattmann ME, Blackwell HE. Geske GD, et al. Among authors: blackwell he. J Am Chem Soc. 2007 Nov 7;129(44):13613-25. doi: 10.1021/ja074135h. Epub 2007 Oct 10. J Am Chem Soc. 2007. PMID: 17927181 Free PMC article.

5

Synthetic ligands that activate and inhibit a quorum-sensing regulator in Pseudomonas aeruginosa.

Mattmann ME, Geske GD, Worzalla GA, Chandler JR, Sappington KJ, Greenberg EP, Blackwell HE. Mattmann ME, et al. Among authors: blackwell he. Bioorg Med Chem Lett. 2008 May 15;18(10):3072-5. doi: 10.1016/j.bmcl.2007.11.095. Epub 2007 Nov 28. Bioorg Med Chem Lett. 2008. PMID: 18083553

6

Comparative analyses of N-acylated homoserine lactones reveal unique structural features that dictate their ability to activate or inhibit quorum sensing.

Geske GD, O'Neill JC, Miller DM, Wezeman RJ, Mattmann ME, Lin Q, Blackwell HE. Geske GD, et al. Among authors: blackwell he. Chembiochem. 2008 Feb 15;9(3):389-400. doi: 10.1002/cbic.200700551. Chembiochem. 2008. PMID: 18224645 Free PMC article.

7

Expanding dialogues: from natural autoinducers to non-natural analogues that modulate quorum sensing in Gram-negative bacteria.

Geske GD, O'Neill JC, Blackwell HE. Geske GD, et al. Among authors: blackwell he. Chem Soc Rev. 2008 Jul;37(7):1432-47. doi: 10.1039/b703021p. Epub 2008 Jun 2. Chem Soc Rev. 2008. PMID: 18568169 Free PMC article. Review.

8

Quorum-sensing signals in the microbial community of the cabbage white butterfly larval midgut.

Borlee BR, Geske GD, Robinson CJ, Blackwell HE, Handelsman J. Borlee BR, et al. Among authors: blackwell he. ISME J. 2008 Nov;2(11):1101-11. doi: 10.1038/ismej.2008.70. Epub 2008 Jul 24. ISME J. 2008. PMID: 18650927 Free PMC article.

9

Evaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulators.

Geske GD, Mattmann ME, Blackwell HE. Geske GD, et al. Among authors: blackwell he. Bioorg Med Chem Lett. 2008 Nov 15;18(22):5978-81. doi: 10.1016/j.bmcl.2008.07.089. Epub 2008 Jul 26. Bioorg Med Chem Lett. 2008. PMID: 18760602 Free PMC article.

10

Efficient synthesis and evaluation of quorum-sensing modulators using small molecule macroarrays.

Praneenararat T, Geske GD, Blackwell HE. Praneenararat T, et al. Among authors: blackwell he. Org Lett. 2009 Oct 15;11(20):4600-3. doi: 10.1021/ol901871y. Org Lett. 2009. PMID: 19743816 Free PMC article.

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