Meng F - Search Results

1

Identification of Novel Disruptor of Telomeric Silencing 1-like (DOT1L) Inhibitors through Structure-Based Virtual Screening and Biological Assays.

Chen S, Li L, Chen Y, Hu J, Liu J, Liu YC, Liu R, Zhang Y, Meng F, Zhu K, Lu J, Zheng M, Chen K, Zhang J, Jiang H, Yao Z, Luo C. Chen S, et al. Among authors: meng f. J Chem Inf Model. 2016 Mar 28;56(3):527-34. doi: 10.1021/acs.jcim.5b00738. Epub 2016 Mar 4. J Chem Inf Model. 2016. PMID: 26914852

2

PTP1B inhibitors from stems of Angelica keiskei (Ashitaba).

Li JL, Gao LX, Meng FW, Tang CL, Zhang RJ, Li JY, Luo C, Li J, Zhao WM. Li JL, et al. Bioorg Med Chem Lett. 2015;25(10):2028-32. doi: 10.1016/j.bmcl.2015.04.003. Epub 2015 Apr 4. Bioorg Med Chem Lett. 2015. PMID: 25891102

3

Discovery and Optimization of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Pharmacophore- and Docking-Based Virtual Screening.

Meng F, Cheng S, Ding H, Liu S, Liu Y, Zhu K, Chen S, Lu J, Xie Y, Li L, Liu R, Shi Z, Zhou Y, Liu YC, Zheng M, Jiang H, Lu W, Liu H, Luo C. Meng F, et al. J Med Chem. 2015 Oct 22;58(20):8166-81. doi: 10.1021/acs.jmedchem.5b01154. Epub 2015 Sep 30. J Med Chem. 2015. PMID: 26390175

4

Plantadeprate A, a Tricyclic Monoterpene Zwitterionic Guanidium, and Related Derivatives from the Seeds of Plantago depressa.

Zheng XM, Meng FW, Geng F, Qi M, Luo C, Yang L, Wang ZT. Zheng XM, et al. Among authors: meng fw. J Nat Prod. 2015 Nov 25;78(11):2822-6. doi: 10.1021/acs.jnatprod.5b00368. Epub 2015 Nov 12. J Nat Prod. 2015. PMID: 26562611

5

Discovery of 3-(5'-Substituted)-Benzimidazole-5-(1-(3,5-dichloropyridin-4-yl)ethoxy)-1H-indazoles as Potent Fibroblast Growth Factor Receptor Inhibitors: Design, Synthesis, and Biological Evaluation.

Yan W, Wang X, Dai Y, Zhao B, Yang X, Fan J, Gao Y, Meng F, Wang Y, Luo C, Ai J, Geng M, Duan W. Yan W, et al. Among authors: meng f. J Med Chem. 2016 Jul 28;59(14):6690-708. doi: 10.1021/acs.jmedchem.6b00056. Epub 2016 Jul 6. J Med Chem. 2016. PMID: 27348537

6

Identification and Characterizations of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Scaffold Hopping- and 2D-Molecular Fingerprint-Based Similarity Search.

Ding H, Lu WC, Hu JC, Liu YC, Zhang CH, Lian FL, Zhang NX, Meng FW, Luo C, Chen KX. Ding H, et al. Molecules. 2018 Mar 2;23(3):567. doi: 10.3390/molecules23030567. Molecules. 2018. PMID: 29498708 Free PMC article.

7

Machine Learning Methods in Precision Medicine Targeting Epigenetic Diseases.

Fan S, Chen Y, Luo C, Meng F. Fan S, et al. Among authors: meng f. Curr Pharm Des. 2018;24(34):3998-4006. doi: 10.2174/1381612824666181112114228. Curr Pharm Des. 2018. PMID: 30421670 Review.

8

The dynamic conformational landscape of the protein methyltransferase SETD8.

Chen S, Wiewiora RP, Meng F, Babault N, Ma A, Yu W, Qian K, Hu H, Zou H, Wang J, Fan S, Blum G, Pittella-Silva F, Beauchamp KA, Tempel W, Jiang H, Chen K, Skene RJ, Zheng YG, Brown PJ, Jin J, Luo C, Chodera JD, Luo M. Chen S, et al. Among authors: meng f. Elife. 2019 May 13;8:e45403. doi: 10.7554/eLife.45403. Elife. 2019. PMID: 31081496 Free PMC article.

9

Drug design targeting active posttranslational modification protein isoforms.

Meng F, Liang Z, Zhao K, Luo C. Meng F, et al. Med Res Rev. 2021 May;41(3):1701-1750. doi: 10.1002/med.21774. Epub 2020 Dec 23. Med Res Rev. 2021. PMID: 33355944 Review.

10

Dynamics of Post-Translational Modification Inspires Drug Design in the Kinase Family.

Zhang H, He J, Hu G, Zhu F, Jiang H, Gao J, Zhou H, Lin H, Wang Y, Chen K, Meng F, Hao M, Zhao K, Luo C, Liang Z. Zhang H, et al. Among authors: meng f. J Med Chem. 2021 Oct 28;64(20):15111-15125. doi: 10.1021/acs.jmedchem.1c01076. Epub 2021 Oct 20. J Med Chem. 2021. PMID: 34668699

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