Reynen P - Search Results

1

Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design.

Volgraf M, Sellers BD, Jiang Y, Wu G, Ly CQ, Villemure E, Pastor RM, Yuen PW, Lu A, Luo X, Liu M, Zhang S, Sun L, Fu Y, Lupardus PJ, Wallweber HJ, Liederer BM, Deshmukh G, Plise E, Tay S, Reynen P, Herrington J, Gustafson A, Liu Y, Dirksen A, Dietz MG, Liu Y, Wang TM, Hanson JE, Hackos D, Scearce-Levie K, Schwarz JB. Volgraf M, et al. Among authors: reynen p. J Med Chem. 2016 Mar 24;59(6):2760-79. doi: 10.1021/acs.jmedchem.5b02010. Epub 2016 Mar 8. J Med Chem. 2016. PMID: 26919761

2

Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function.

Hackos DH, Lupardus PJ, Grand T, Chen Y, Wang TM, Reynen P, Gustafson A, Wallweber HJ, Volgraf M, Sellers BD, Schwarz JB, Paoletti P, Sheng M, Zhou Q, Hanson JE. Hackos DH, et al. Among authors: reynen p. Neuron. 2016 Mar 2;89(5):983-99. doi: 10.1016/j.neuron.2016.01.016. Epub 2016 Feb 11. Neuron. 2016. PMID: 26875626 Free article.

3

Chronic GluN2B antagonism disrupts behavior in wild-type mice without protecting against synapse loss or memory impairment in Alzheimer's disease mouse models.

Hanson JE, Meilandt WJ, Gogineni A, Reynen P, Herrington J, Weimer RM, Scearce-Levie K, Zhou Q. Hanson JE, et al. Among authors: reynen p. J Neurosci. 2014 Jun 11;34(24):8277-88. doi: 10.1523/JNEUROSCI.5106-13.2014. J Neurosci. 2014. PMID: 24920631 Free PMC article.

4

The GluN2B subunit represents a major functional determinant of NMDA receptors in human induced pluripotent stem cell-derived cortical neurons.

Neagoe I, Liu C, Stumpf A, Lu Y, He D, Francis R, Chen J, Reynen P, Alaoui-Ismaili MH, Fukui H. Neagoe I, et al. Among authors: reynen p. Stem Cell Res. 2018 Apr;28:105-114. doi: 10.1016/j.scr.2018.02.002. Epub 2018 Feb 8. Stem Cell Res. 2018. PMID: 29454156 Free article.

5

Evidence for inverse agonism of SR141716A at human recombinant cannabinoid CB1 and CB2 receptors.

MacLennan SJ, Reynen PH, Kwan J, Bonhaus DW. MacLennan SJ, et al. Among authors: reynen ph. Br J Pharmacol. 1998 Jun;124(4):619-22. doi: 10.1038/sj.bjp.0701915. Br J Pharmacol. 1998. PMID: 9690851 Free PMC article.

6

Pharmacological comparison of a recombinant CB1 cannabinoid receptor with its G(alpha 16) fusion product.

Martin RS, Reynen PH, Calixto JJ, Reyes CL, Chang TK, Dietrich PS, Bonhaus DW, MacLennan SJ. Martin RS, et al. Among authors: reynen ph. J Biomol Screen. 2002 Jun;7(3):281-9. doi: 10.1177/108705710200700312. J Biomol Screen. 2002. PMID: 12097191

7

Characterization of human recombinant alpha(2A)-adrenoceptors expressed in Chinese hamster lung cells using extracellular acidification rate changes.

MacLennan SJ, Reynen PH, Martin RS, Eglen RM, Martin GR. MacLennan SJ, et al. Among authors: reynen ph. Br J Pharmacol. 2000 Apr;129(7):1333-8. doi: 10.1038/sj.bjp.0703183. Br J Pharmacol. 2000. PMID: 10742288 Free PMC article.

8

Characterization of human recombinant alpha(2A)-adrenoceptors expressed in Chinese hamster lung cells using intracellular Ca(2+) changes: evidence for cross-talk between recombinant alpha(2A)- and native alpha(1)-adrenoceptors.

Reynen PH, Martin GR, Eglen RM, MacLennan SJ. Reynen PH, et al. Br J Pharmacol. 2000 Apr;129(7):1339-46. doi: 10.1038/sj.bjp.0703184. Br J Pharmacol. 2000. PMID: 10742289 Free PMC article.

9

MIS-C vs Incomplete Kawasaki's Disease in a 12-year-old Female: A Case Study.

Morris KR, Hemmer AM, Sievers ME, VanKalsbeek MB, Reynen PJ. Morris KR, et al. Among authors: reynen pj. S D Med. 2024 Mar;77(3):120-126. S D Med. 2024. PMID: 38990796

10

A Case of Neurocysticercosis in Rural South Dakota.

Merrill L, Hurd A, Hohn L, Reynen P. Merrill L, et al. Among authors: reynen p. S D Med. 2023 Aug;76(8):353-356. S D Med. 2023. PMID: 37734078

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