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98 results

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A Phase I Study of Quizartinib Combined with Chemotherapy in Relapsed Childhood Leukemia: A Therapeutic Advances in Childhood Leukemia & Lymphoma (TACL) Study.
Cooper TM, Cassar J, Eckroth E, Malvar J, Sposto R, Gaynon P, Chang BH, Gore L, August K, Pollard JA, DuBois SG, Silverman LB, Oesterheld J, Gammon G, Magoon D, Annesley C, Brown PA. Cooper TM, et al. Among authors: gammon g. Clin Cancer Res. 2016 Aug 15;22(16):4014-22. doi: 10.1158/1078-0432.CCR-15-1998. Epub 2016 Feb 26. Clin Cancer Res. 2016. PMID: 26920889 Clinical Trial.
Phase I study of quizartinib administered daily to patients with relapsed or refractory acute myeloid leukemia irrespective of FMS-like tyrosine kinase 3-internal tandem duplication status.
Cortes JE, Kantarjian H, Foran JM, Ghirdaladze D, Zodelava M, Borthakur G, Gammon G, Trone D, Armstrong RC, James J, Levis M. Cortes JE, et al. Among authors: gammon g. J Clin Oncol. 2013 Oct 10;31(29):3681-7. doi: 10.1200/JCO.2013.48.8783. Epub 2013 Sep 3. J Clin Oncol. 2013. PMID: 24002496 Free PMC article. Clinical Trial.
Clinical Outcomes in Patients with FLT3-ITD-Mutated Relapsed/Refractory Acute Myelogenous Leukemia Undergoing Hematopoietic Stem Cell Transplantation after Quizartinib or Salvage Chemotherapy in the QuANTUM-R Trial.
Ganguly S, Cortes JE, Krämer A, Levis MJ, Martinelli G, Perl AE, Russell NH, Arunachalam M, Santos CD, Gammon G, Lesegretain A, Mires DE, Pham H, Wang Y, Khaled SK. Ganguly S, et al. Among authors: gammon g. Transplant Cell Ther. 2021 Feb;27(2):153-162. doi: 10.1016/j.bbmt.2020.09.036. Epub 2020 Oct 2. Transplant Cell Ther. 2021. PMID: 33017662 Free article.
Quizartinib, an FLT3 inhibitor, as monotherapy in patients with relapsed or refractory acute myeloid leukaemia: an open-label, multicentre, single-arm, phase 2 trial.
Cortes J, Perl AE, Döhner H, Kantarjian H, Martinelli G, Kovacsovics T, Rousselot P, Steffen B, Dombret H, Estey E, Strickland S, Altman JK, Baldus CD, Burnett A, Krämer A, Russell N, Shah NP, Smith CC, Wang ES, Ifrah N, Gammon G, Trone D, Lazzaretto D, Levis M. Cortes J, et al. Among authors: gammon g. Lancet Oncol. 2018 Jul;19(7):889-903. doi: 10.1016/S1470-2045(18)30240-7. Epub 2018 May 31. Lancet Oncol. 2018. PMID: 29859851 Free PMC article. Clinical Trial.
Effect of Food on the Pharmacokinetics of Quizartinib.
Li J, Holmes M, Kankam M, Trone D, Mendell J, Gammon G. Li J, et al. Among authors: gammon g. Clin Pharmacol Drug Dev. 2020 Feb;9(2):277-286. doi: 10.1002/cpdd.770. Epub 2020 Jan 8. Clin Pharmacol Drug Dev. 2020. PMID: 31916418 Free PMC article. Clinical Trial.
An open-label, single-dose, phase 1 study of the absorption, metabolism and excretion of quizartinib, a highly selective and potent FLT3 tyrosine kinase inhibitor, in healthy male subjects, for the treatment of acute myeloid leukemia.
Sanga M, James J, Marini J, Gammon G, Hale C, Li J. Sanga M, et al. Among authors: gammon g. Xenobiotica. 2017 Oct;47(10):856-869. doi: 10.1080/00498254.2016.1217100. Epub 2017 Jul 25. Xenobiotica. 2017. PMID: 27460866 Clinical Trial.
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