Graham BH - Search Results

1

Fatty Acid Oxidation-Driven Src Links Mitochondrial Energy Reprogramming and Oncogenic Properties in Triple-Negative Breast Cancer.

Park JH, Vithayathil S, Kumar S, Sung PL, Dobrolecki LE, Putluri V, Bhat VB, Bhowmik SK, Gupta V, Arora K, Wu D, Tsouko E, Zhang Y, Maity S, Donti TR, Graham BH, Frigo DE, Coarfa C, Yotnda P, Putluri N, Sreekumar A, Lewis MT, Creighton CJ, Wong LC, Kaipparettu BA. Park JH, et al. Among authors: graham bh. Cell Rep. 2016 Mar 8;14(9):2154-2165. doi: 10.1016/j.celrep.2016.02.004. Epub 2016 Feb 25. Cell Rep. 2016. PMID: 26923594 Free PMC article.

2

Screen for abnormal mitochondrial phenotypes in mouse embryonic stem cells identifies a model for succinyl-CoA ligase deficiency and mtDNA depletion.

Donti TR, Stromberger C, Ge M, Eldin KW, Craigen WJ, Graham BH. Donti TR, et al. Among authors: graham bh. Dis Model Mech. 2014 Feb;7(2):271-80. doi: 10.1242/dmm.013466. Epub 2013 Nov 21. Dis Model Mech. 2014. PMID: 24271779 Free PMC article.

3

Increased COUP-TFII expression in adult hearts induces mitochondrial dysfunction resulting in heart failure.

Wu SP, Kao CY, Wang L, Creighton CJ, Yang J, Donti TR, Harmancey R, Vasquez HG, Graham BH, Bellen HJ, Taegtmeyer H, Chang CP, Tsai MJ, Tsai SY. Wu SP, et al. Among authors: graham bh. Nat Commun. 2015 Sep 10;6:8245. doi: 10.1038/ncomms9245. Nat Commun. 2015. PMID: 26356605 Free PMC article.

4

Expanding the phenotypic spectrum of Succinyl-CoA ligase deficiency through functional validation of a new SUCLG1 variant.

Donti TR, Masand R, Scott DA, Craigen WJ, Graham BH. Donti TR, et al. Among authors: graham bh. Mol Genet Metab. 2016 Sep;119(1-2):68-74. doi: 10.1016/j.ymgme.2016.07.007. Epub 2016 Jul 25. Mol Genet Metab. 2016. PMID: 27484306 Free PMC article.

5

Loss of Nardilysin, a Mitochondrial Co-chaperone for α-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and Neurodegeneration.

Yoon WH, Sandoval H, Nagarkar-Jaiswal S, Jaiswal M, Yamamoto S, Haelterman NA, Putluri N, Putluri V, Sreekumar A, Tos T, Aksoy A, Donti T, Graham BH, Ohno M, Nishi E, Hunter J, Muzny DM, Carmichael J, Shen J, Arboleda VA, Nelson SF, Wangler MF, Karaca E, Lupski JR, Bellen HJ. Yoon WH, et al. Among authors: graham bh. Neuron. 2017 Jan 4;93(1):115-131. doi: 10.1016/j.neuron.2016.11.038. Epub 2016 Dec 22. Neuron. 2017. PMID: 28017472 Free PMC article.

6

The GABA transaminase, ABAT, is essential for mitochondrial nucleoside metabolism.

Besse A, Wu P, Bruni F, Donti T, Graham BH, Craigen WJ, McFarland R, Moretti P, Lalani S, Scott KL, Taylor RW, Bonnen PE. Besse A, et al. Among authors: graham bh. Cell Metab. 2015 Mar 3;21(3):417-27. doi: 10.1016/j.cmet.2015.02.008. Cell Metab. 2015. PMID: 25738457 Free PMC article.

7

Peroxisomal biogenesis is genetically and biochemically linked to carbohydrate metabolism in Drosophila and mouse.

Wangler MF, Chao YH, Bayat V, Giagtzoglou N, Shinde AB, Putluri N, Coarfa C, Donti T, Graham BH, Faust JE, McNew JA, Moser A, Sardiello M, Baes M, Bellen HJ. Wangler MF, et al. Among authors: graham bh. PLoS Genet. 2017 Jun 22;13(6):e1006825. doi: 10.1371/journal.pgen.1006825. eCollection 2017 Jun. PLoS Genet. 2017. PMID: 28640802 Free PMC article.

8

Impaired Mitochondrial Energy Production Causes Light-Induced Photoreceptor Degeneration Independent of Oxidative Stress.

Jaiswal M, Haelterman NA, Sandoval H, Xiong B, Donti T, Kalsotra A, Yamamoto S, Cooper TA, Graham BH, Bellen HJ. Jaiswal M, et al. Among authors: graham bh. PLoS Biol. 2015 Jul 15;13(7):e1002197. doi: 10.1371/journal.pbio.1002197. eCollection 2015 Jul. PLoS Biol. 2015. PMID: 26176594 Free PMC article.

9

Functional cellular analyses reveal energy metabolism defect and mitochondrial DNA depletion in a case of mitochondrial aconitase deficiency.

Sadat R, Barca E, Masand R, Donti TR, Naini A, De Vivo DC, DiMauro S, Hanchard NA, Graham BH. Sadat R, et al. Among authors: graham bh. Mol Genet Metab. 2016 May;118(1):28-34. doi: 10.1016/j.ymgme.2016.03.004. Epub 2016 Mar 8. Mol Genet Metab. 2016. PMID: 26992325 Free PMC article.

10

Mitochondrial Dysfunction Mediated by Poly(ADP-Ribose) Polymerase-1 Activation Contributes to Hippocampal Neuronal Damage Following Status Epilepticus.

Lai YC, Baker JS, Donti T, Graham BH, Craigen WJ, Anderson AE. Lai YC, et al. Among authors: graham bh. Int J Mol Sci. 2017 Jul 12;18(7):1502. doi: 10.3390/ijms18071502. Int J Mol Sci. 2017. PMID: 28704930 Free PMC article.

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