Messias AC - Search Results

1

Novel small molecules targeting ciliary transport of Smoothened and oncogenic Hedgehog pathway activation.

Jung B, Messias AC, Schorpp K, Geerlof A, Schneider G, Saur D, Hadian K, Sattler M, Wanker EE, Hasenöder S, Lickert H. Jung B, et al. Among authors: messias ac. Sci Rep. 2016 Mar 2;6:22540. doi: 10.1038/srep22540. Sci Rep. 2016. PMID: 26931153 Free PMC article.

2

Structural basis of single-stranded RNA recognition.

Messias AC, Sattler M. Messias AC, et al. Acc Chem Res. 2004 May;37(5):279-87. doi: 10.1021/ar030034m. Acc Chem Res. 2004. PMID: 15147168 Review.

3

The DICE-binding activity of KH domain 3 of hnRNP K is affected by c-Src-mediated tyrosine phosphorylation.

Messias AC, Harnisch C, Ostareck-Lederer A, Sattler M, Ostareck DH. Messias AC, et al. J Mol Biol. 2006 Aug 18;361(3):470-81. doi: 10.1016/j.jmb.2006.06.025. Epub 2006 Jun 30. J Mol Biol. 2006. PMID: 16854432

4

Novel biomarkers for pre-diabetes identified by metabolomics.

Wang-Sattler R, Yu Z, Herder C, Messias AC, Floegel A, He Y, Heim K, Campillos M, Holzapfel C, Thorand B, Grallert H, Xu T, Bader E, Huth C, Mittelstrass K, Döring A, Meisinger C, Gieger C, Prehn C, Roemisch-Margl W, Carstensen M, Xie L, Yamanaka-Okumura H, Xing G, Ceglarek U, Thiery J, Giani G, Lickert H, Lin X, Li Y, Boeing H, Joost HG, de Angelis MH, Rathmann W, Suhre K, Prokisch H, Peters A, Meitinger T, Roden M, Wichmann HE, Pischon T, Adamski J, Illig T. Wang-Sattler R, et al. Among authors: messias ac. Mol Syst Biol. 2012;8:615. doi: 10.1038/msb.2012.43. Mol Syst Biol. 2012. PMID: 23010998 Free PMC article.

5

Structural Characterization of LRRK2 Inhibitors.

Gilsbach BK, Messias AC, Ito G, Sattler M, Alessi DR, Wittinghofer A, Kortholt A. Gilsbach BK, et al. Among authors: messias ac. J Med Chem. 2015 May 14;58(9):3751-6. doi: 10.1021/jm5018779. Epub 2015 May 1. J Med Chem. 2015. PMID: 25897865

6

Inhibition of Canonical NF-κB Signaling by a Small Molecule Targeting NEMO-Ubiquitin Interaction.

Vincendeau M, Hadian K, Messias AC, Brenke JK, Halander J, Griesbach R, Greczmiel U, Bertossi A, Stehle R, Nagel D, Demski K, Velvarska H, Niessing D, Geerlof A, Sattler M, Krappmann D. Vincendeau M, et al. Among authors: messias ac. Sci Rep. 2016 Jan 7;6:18934. doi: 10.1038/srep18934. Sci Rep. 2016. PMID: 26740240 Free PMC article.

7

Pitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway Activation.

Jung B, Padula D, Burtscher I, Landerer C, Lutter D, Theis F, Messias AC, Geerlof A, Sattler M, Kremmer E, Boldt K, Ueffing M, Lickert H. Jung B, et al. Among authors: messias ac. PLoS One. 2016 Feb 22;11(2):e0149477. doi: 10.1371/journal.pone.0149477. eCollection 2016. PLoS One. 2016. PMID: 26901434 Free PMC article.

8

Celastrol-Induced Weight Loss Is Driven by Hypophagia and Independent From UCP1.

Pfuhlmann K, Schriever SC, Baumann P, Kabra DG, Harrison L, Mazibuko-Mbeje SE, Contreras RE, Kyriakou E, Simonds SE, Tiganis T, Cowley MA, Woods SC, Jastroch M, Clemmensen C, De Angelis M, Schramm KW, Sattler M, Messias AC, Tschöp MH, Pfluger PT. Pfuhlmann K, et al. Among authors: messias ac. Diabetes. 2018 Nov;67(11):2456-2465. doi: 10.2337/db18-0146. Epub 2018 Aug 28. Diabetes. 2018. PMID: 30158241

9

The Structure of the SPOP-Pdx1 Interface Reveals Insights into the Phosphorylation-Dependent Binding Regulation.

Ostertag MS, Messias AC, Sattler M, Popowicz GM. Ostertag MS, et al. Among authors: messias ac. Structure. 2019 Feb 5;27(2):327-334.e3. doi: 10.1016/j.str.2018.10.005. Epub 2018 Nov 15. Structure. 2019. PMID: 30449689 Free article.

10

Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus.

Kyriakou E, Schmidt S, Dodd GT, Pfuhlmann K, Simonds SE, Lenhart D, Geerlof A, Schriever SC, De Angelis M, Schramm KW, Plettenburg O, Cowley MA, Tiganis T, Tschöp MH, Pfluger PT, Sattler M, Messias AC. Kyriakou E, et al. Among authors: messias ac. J Med Chem. 2018 Dec 27;61(24):11144-11157. doi: 10.1021/acs.jmedchem.8b01224. Epub 2018 Dec 7. J Med Chem. 2018. PMID: 30525586

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