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Page 1
Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys.
Warren TK, Jordan R, Lo MK, Ray AS, Mackman RL, Soloveva V, Siegel D, Perron M, Bannister R, Hui HC, Larson N, Strickley R, Wells J, Stuthman KS, Van Tongeren SA, Garza NL, Donnelly G, Shurtleff AC, Retterer CJ, Gharaibeh D, Zamani R, Kenny T, Eaton BP, Grimes E, Welch LS, Gomba L, Wilhelmsen CL, Nichols DK, Nuss JE, Nagle ER, Kugelman JR, Palacios G, Doerffler E, Neville S, Carra E, Clarke MO, Zhang L, Lew W, Ross B, Wang Q, Chun K, Wolfe L, Babusis D, Park Y, Stray KM, Trancheva I, Feng JY, Barauskas O, Xu Y, Wong P, Braun MR, Flint M, McMullan LK, Chen SS, Fearns R, Swaminathan S, Mayers DL, Spiropoulou CF, Lee WA, Nichol ST, Cihlar T, Bavari S. Warren TK, et al. Among authors: soloveva v. Nature. 2016 Mar 17;531(7594):381-5. doi: 10.1038/nature17180. Epub 2016 Mar 2. Nature. 2016. PMID: 26934220 Free PMC article.
Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses.
Siegel D, Hui HC, Doerffler E, Clarke MO, Chun K, Zhang L, Neville S, Carra E, Lew W, Ross B, Wang Q, Wolfe L, Jordan R, Soloveva V, Knox J, Perry J, Perron M, Stray KM, Barauskas O, Feng JY, Xu Y, Lee G, Rheingold AL, Ray AS, Bannister R, Strickley R, Swaminathan S, Lee WA, Bavari S, Cihlar T, Lo MK, Warren TK, Mackman RL. Siegel D, et al. Among authors: soloveva v. J Med Chem. 2017 Mar 9;60(5):1648-1661. doi: 10.1021/acs.jmedchem.6b01594. Epub 2017 Feb 14. J Med Chem. 2017. PMID: 28124907
Flex-nucleoside analogues - Novel therapeutics against filoviruses.
Yates MK, Raje MR, Chatterjee P, Spiropoulou CF, Bavari S, Flint M, Soloveva V, Seley-Radtke KL. Yates MK, et al. Among authors: soloveva v. Bioorg Med Chem Lett. 2017 Jun 15;27(12):2800-2802. doi: 10.1016/j.bmcl.2017.04.069. Epub 2017 Apr 22. Bioorg Med Chem Lett. 2017. PMID: 28465098 Free PMC article.
Intracellular conversion and in vivo dose response of favipiravir (T-705) in rodents infected with Ebola virus.
Bixler SL, Bocan TM, Wells J, Wetzel KS, Van Tongeren SA, Garza NL, Donnelly G, Cazares LH, Soloveva V, Welch L, Epstein C, Liang LF, Giesing D, Lenk R, Bavari S, Warren TK. Bixler SL, et al. Among authors: soloveva v. Antiviral Res. 2018 Mar;151:50-54. doi: 10.1016/j.antiviral.2017.12.020. Epub 2017 Dec 28. Antiviral Res. 2018. PMID: 29289664 Free article.
Efficacy of favipiravir (T-705) in nonhuman primates infected with Ebola virus or Marburg virus.
Bixler SL, Bocan TM, Wells J, Wetzel KS, Van Tongeren SA, Dong L, Garza NL, Donnelly G, Cazares LH, Nuss J, Soloveva V, Koistinen KA, Welch L, Epstein C, Liang LF, Giesing D, Lenk R, Bavari S, Warren TK. Bixler SL, et al. Among authors: soloveva v. Antiviral Res. 2018 Mar;151:97-104. doi: 10.1016/j.antiviral.2017.12.021. Epub 2017 Dec 28. Antiviral Res. 2018. PMID: 29289666 Free article.
Cholesterol-conjugated stapled peptides inhibit Ebola and Marburg viruses in vitro and in vivo.
Pessi A, Bixler SL, Soloveva V, Radoshitzky S, Retterer C, Kenny T, Zamani R, Gomba G, Gharabeih D, Wells J, Wetzel KS, Warren TK, Donnelly G, Van Tongeren SA, Steffens J, Duplantier AJ, Kane CD, Vicat P, Couturier V, Kester KE, Shiver J, Carter K, Bavari S. Pessi A, et al. Among authors: soloveva v. Antiviral Res. 2019 Nov;171:104592. doi: 10.1016/j.antiviral.2019.104592. Epub 2019 Aug 29. Antiviral Res. 2019. PMID: 31473342 Free article.
Intensive Care Unit-Like Care of Nonhuman Primates with Ebola Virus Disease.
Blair PW, Kortepeter MG, Downey LG, Madar CS, Downs IL, Martins KA, Rossi F, Williams JA, Madar A, Schellhase CW, Bearss JJ, Zeng X, Bavari S, Soloveva V, Wells JB, Stuthman KS, Garza NL, Vantongeren SA, Donnelly GC, Steffens J, Kalapaca J, Wiseman P, Henry J, Marko S, Chappell M, Lugo-Roman L, Ramos-Rivera E, Hofer C, Blue E, Moore J, Fiallos J, Wetzel D, Pratt WD, Unangst T, Miller A, Sola JJ, Reisler RB, Cardile AP. Blair PW, et al. Among authors: soloveva v. J Infect Dis. 2021 Aug 16;224(4):632-642. doi: 10.1093/infdis/jiaa781. J Infect Dis. 2021. PMID: 33367826 Free PMC article.
Anti-Ebola Activity of Diazachrysene Small Molecules.
Selaković Ž, Soloveva V, Gharaibeh DN, Wells J, Šegan S, Panchal RG, Šolaja BA. Selaković Ž, et al. Among authors: soloveva v. ACS Infect Dis. 2015 Jun 12;1(6):264-71. doi: 10.1021/acsinfecdis.5b00028. Epub 2015 May 4. ACS Infect Dis. 2015. PMID: 27622742
Discovery of Novel Small-Molecule Inhibitors of LIM Domain Kinase for Inhibiting HIV-1.
Yi F, Guo J, Dabbagh D, Spear M, He S, Kehn-Hall K, Fontenot J, Yin Y, Bibian M, Park CM, Zheng K, Park HJ, Soloveva V, Gharaibeh D, Retterer C, Zamani R, Pitt ML, Naughton J, Jiang Y, Shang H, Hakami RM, Ling B, Young JAT, Bavari S, Xu X, Feng Y, Wu Y. Yi F, et al. Among authors: soloveva v. J Virol. 2017 Jun 9;91(13):e02418-16. doi: 10.1128/JVI.02418-16. Print 2017 Jul 1. J Virol. 2017. PMID: 28381571 Free PMC article.
132 results