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Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys.
Warren TK, Jordan R, Lo MK, Ray AS, Mackman RL, Soloveva V, Siegel D, Perron M, Bannister R, Hui HC, Larson N, Strickley R, Wells J, Stuthman KS, Van Tongeren SA, Garza NL, Donnelly G, Shurtleff AC, Retterer CJ, Gharaibeh D, Zamani R, Kenny T, Eaton BP, Grimes E, Welch LS, Gomba L, Wilhelmsen CL, Nichols DK, Nuss JE, Nagle ER, Kugelman JR, Palacios G, Doerffler E, Neville S, Carra E, Clarke MO, Zhang L, Lew W, Ross B, Wang Q, Chun K, Wolfe L, Babusis D, Park Y, Stray KM, Trancheva I, Feng JY, Barauskas O, Xu Y, Wong P, Braun MR, Flint M, McMullan LK, Chen SS, Fearns R, Swaminathan S, Mayers DL, Spiropoulou CF, Lee WA, Nichol ST, Cihlar T, Bavari S. Warren TK, et al. Among authors: zamani r. Nature. 2016 Mar 17;531(7594):381-5. doi: 10.1038/nature17180. Epub 2016 Mar 2. Nature. 2016. PMID: 26934220 Free PMC article.
Bithionol blocks pathogenicity of bacterial toxins, ricin, and Zika virus.
Leonardi W, Zilbermintz L, Cheng LW, Zozaya J, Tran SH, Elliott JH, Polukhina K, Manasherob R, Li A, Chi X, Gharaibeh D, Kenny T, Zamani R, Soloveva V, Haddow AD, Nasar F, Bavari S, Bassik MC, Cohen SN, Levitin A, Martchenko M. Leonardi W, et al. Among authors: zamani r. Sci Rep. 2016 Sep 30;6:34475. doi: 10.1038/srep34475. Sci Rep. 2016. PMID: 27686742 Free PMC article.
Discovery of Novel Small-Molecule Inhibitors of LIM Domain Kinase for Inhibiting HIV-1.
Yi F, Guo J, Dabbagh D, Spear M, He S, Kehn-Hall K, Fontenot J, Yin Y, Bibian M, Park CM, Zheng K, Park HJ, Soloveva V, Gharaibeh D, Retterer C, Zamani R, Pitt ML, Naughton J, Jiang Y, Shang H, Hakami RM, Ling B, Young JAT, Bavari S, Xu X, Feng Y, Wu Y. Yi F, et al. Among authors: zamani r. J Virol. 2017 Jun 9;91(13):e02418-16. doi: 10.1128/JVI.02418-16. Print 2017 Jul 1. J Virol. 2017. PMID: 28381571 Free PMC article.
Cholesterol-conjugated stapled peptides inhibit Ebola and Marburg viruses in vitro and in vivo.
Pessi A, Bixler SL, Soloveva V, Radoshitzky S, Retterer C, Kenny T, Zamani R, Gomba G, Gharabeih D, Wells J, Wetzel KS, Warren TK, Donnelly G, Van Tongeren SA, Steffens J, Duplantier AJ, Kane CD, Vicat P, Couturier V, Kester KE, Shiver J, Carter K, Bavari S. Pessi A, et al. Among authors: zamani r. Antiviral Res. 2019 Nov;171:104592. doi: 10.1016/j.antiviral.2019.104592. Epub 2019 Aug 29. Antiviral Res. 2019. PMID: 31473342 Free article.
siRNA Screen Identifies Trafficking Host Factors that Modulate Alphavirus Infection.
Radoshitzky SR, Pegoraro G, Chī XO, D Ng L, Chiang CY, Jozwick L, Clester JC, Cooper CL, Courier D, Langan DP, Underwood K, Kuehl KA, Sun MG, Caì Y, Yú SQ, Burk R, Zamani R, Kota K, Kuhn JH, Bavari S. Radoshitzky SR, et al. Among authors: zamani r. PLoS Pathog. 2016 Mar 31;12(3):e1005466. doi: 10.1371/journal.ppat.1005466. eCollection 2016 Mar. PLoS Pathog. 2016. PMID: 27031835 Free PMC article.
106 results