van Lummel M - Search Results

1

Dendritic Cells Guide Islet Autoimmunity through a Restricted and Uniquely Processed Peptidome Presented by High-Risk HLA-DR.

van Lummel M, van Veelen PA, de Ru AH, Janssen GM, Pool J, Laban S, Joosten AM, Nikolic T, Drijfhout JW, Mearin ML, Aanstoot HJ, Peakman M, Roep BO. van Lummel M, et al. J Immunol. 2016 Apr 15;196(8):3253-63. doi: 10.4049/jimmunol.1501282. Epub 2016 Mar 4. J Immunol. 2016. PMID: 26944932

2

Gluten-specific T cells cross-react between HLA-DQ8 and the HLA-DQ2α/DQ8β transdimer.

Kooy-Winkelaar Y, van Lummel M, Moustakas AK, Schweizer J, Mearin ML, Mulder CJ, Roep BO, Drijfhout JW, Papadopoulos GK, van Bergen J, Koning F. Kooy-Winkelaar Y, et al. Among authors: van lummel m, van bergen j. J Immunol. 2011 Nov 15;187(10):5123-9. doi: 10.4049/jimmunol.1101179. Epub 2011 Oct 17. J Immunol. 2011. PMID: 22013116

3

Posttranslational modification of HLA-DQ binding islet autoantigens in type 1 diabetes.

van Lummel M, Duinkerken G, van Veelen PA, de Ru A, Cordfunke R, Zaldumbide A, Gomez-Touriño I, Arif S, Peakman M, Drijfhout JW, Roep BO. van Lummel M, et al. Among authors: van veelen pa. Diabetes. 2014 Jan;63(1):237-47. doi: 10.2337/db12-1214. Epub 2013 Oct 2. Diabetes. 2014. PMID: 24089515

4

Discovery of a Selective Islet Peptidome Presented by the Highest-Risk HLA-DQ8trans Molecule.

van Lummel M, van Veelen PA, de Ru AH, Pool J, Nikolic T, Laban S, Joosten A, Drijfhout JW, Gómez-Touriño I, Arif S, Aanstoot HJ, Peakman M, Roep BO. van Lummel M, et al. Diabetes. 2016 Mar;65(3):732-41. doi: 10.2337/db15-1031. Epub 2015 Dec 30. Diabetes. 2016. PMID: 26718497

5

Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes.

Kracht MJ, van Lummel M, Nikolic T, Joosten AM, Laban S, van der Slik AR, van Veelen PA, Carlotti F, de Koning EJ, Hoeben RC, Zaldumbide A, Roep BO. Kracht MJ, et al. Among authors: van lummel m. Nat Med. 2017 Apr;23(4):501-507. doi: 10.1038/nm.4289. Epub 2017 Feb 27. Nat Med. 2017. PMID: 28263308

6

Epitope Stealing as a Mechanism of Dominant Protection by HLA-DQ6 in Type 1 Diabetes.

van Lummel M, Buis DTP, Ringeling C, de Ru AH, Pool J, Papadopoulos GK, van Veelen PA, Reijonen H, Drijfhout JW, Roep BO. van Lummel M, et al. Diabetes. 2019 Apr;68(4):787-795. doi: 10.2337/db18-0501. Epub 2019 Jan 9. Diabetes. 2019. PMID: 30626607

7

Human islets and dendritic cells generate post-translationally modified islet autoantigens.

McLaughlin RJ, de Haan A, Zaldumbide A, de Koning EJ, de Ru AH, van Veelen PA, van Lummel M, Roep BO. McLaughlin RJ, et al. Among authors: van lummel m. Clin Exp Immunol. 2016 Aug;185(2):133-40. doi: 10.1111/cei.12775. Epub 2016 May 17. Clin Exp Immunol. 2016. PMID: 26861694 Free PMC article.

8

Type 1 diabetes-associated HLA-DQ8 transdimer accommodates a unique peptide repertoire.

van Lummel M, van Veelen PA, Zaldumbide A, de Ru A, Janssen GM, Moustakas AK, Papadopoulos GK, Drijfhout JW, Roep BO, Koning F. van Lummel M, et al. Among authors: van veelen pa. J Biol Chem. 2012 Mar 16;287(12):9514-24. doi: 10.1074/jbc.M111.313940. Epub 2011 Dec 19. J Biol Chem. 2012. PMID: 22184118 Free PMC article.

9

Changing faces, unmasking the beta-cell: post-translational modification of antigens in type 1 diabetes.

van Lummel M, Zaldumbide A, Roep BO. van Lummel M, et al. Curr Opin Endocrinol Diabetes Obes. 2013 Aug;20(4):299-306. doi: 10.1097/MED.0b013e3283631417. Curr Opin Endocrinol Diabetes Obes. 2013. PMID: 23770733 Review.

10

Where, How, and When: Positioning Posttranslational Modification Within Type 1 Diabetes Pathogenesis.

McLaughlin RJ, Spindler MP, van Lummel M, Roep BO. McLaughlin RJ, et al. Among authors: van lummel m. Curr Diab Rep. 2016 Jul;16(7):63. doi: 10.1007/s11892-016-0752-4. Curr Diab Rep. 2016. PMID: 27168063 Free PMC article. Review.

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