Dekker RJ - Search Results

1

LNA modification of single-stranded DNA oligonucleotides allows subtle gene modification in mismatch-repair-proficient cells.

van Ravesteyn TW, Dekker M, Fish A, Sixma TK, Wolters A, Dekker RJ, Te Riele HP. van Ravesteyn TW, et al. Among authors: dekker rj. Proc Natl Acad Sci U S A. 2016 Apr 12;113(15):4122-7. doi: 10.1073/pnas.1513315113. Epub 2016 Mar 7. Proc Natl Acad Sci U S A. 2016. PMID: 26951689 Free PMC article.

2

Gene modification in embryonic stem cells by single-stranded DNA oligonucleotides.

Aarts M, Dekker M, Dekker R, de Vries S, van der Wal A, Wielders E, Riele HT. Aarts M, et al. Methods Mol Biol. 2009;530:79-99. doi: 10.1007/978-1-59745-471-1_5. Methods Mol Biol. 2009. PMID: 19266328

3

Characterization of MSH2 variants by endogenous gene modification in mouse embryonic stem cells.

Wielders EA, Dekker RJ, Holt I, Morris GE, te Riele H. Wielders EA, et al. Among authors: dekker rj. Hum Mutat. 2011 Apr;32(4):389-96. doi: 10.1002/humu.21448. Epub 2011 Mar 8. Hum Mutat. 2011. PMID: 21309037 Free article.

4

Transient suppression of MLH1 allows effective single-nucleotide substitution by single-stranded DNA oligonucleotides.

Dekker M, de Vries S, Aarts M, Dekker R, Brouwers C, Wiebenga O, de Wind N, Cantelli E, Tonelli R, Te Riele H. Dekker M, et al. Mutat Res. 2011 Oct 1;715(1-2):52-60. doi: 10.1016/j.mrfmmm.2011.07.008. Epub 2011 Jul 27. Mutat Res. 2011. PMID: 21801734

5

Functional analysis of MSH2 unclassified variants found in suspected Lynch syndrome patients reveals pathogenicity due to attenuated mismatch repair.

Wielders EA, Hettinger J, Dekker R, Kets CM, Ligtenberg MJ, Mensenkamp AR, van den Ouweland AM, Prins J, Wagner A, Dinjens WN, Dubbink HJ, van Hest LP, Menko F, Hogervorst F, Verhoef S, te Riele H. Wielders EA, et al. J Med Genet. 2014 Apr;51(4):245-53. doi: 10.1136/jmedgenet-2013-101987. Epub 2014 Feb 5. J Med Genet. 2014. PMID: 24501230

6

Truncation of the MSH2 C-terminal 60 amino acids disrupts effective DNA mismatch repair and is causative for Lynch syndrome.

Wielders E, Delzenne-Goette E, Dekker R, van der Valk M, Te Riele H. Wielders E, et al. Fam Cancer. 2017 Apr;16(2):221-229. doi: 10.1007/s10689-016-9945-x. Fam Cancer. 2017. PMID: 27873144

7

The variable region-1 from tissue-type plasminogen activator confers specificity for plasminogen activator inhibitor-1 to thrombin by facilitating catalysis: release of a kinetic block by a heterologous protein surface loop.

Dekker RJ, Eichinger A, Stoop AA, Bode W, Pannekoek H, Horrevoets AJ. Dekker RJ, et al. J Mol Biol. 1999 Oct 29;293(3):613-27. doi: 10.1006/jmbi.1999.3178. J Mol Biol. 1999. PMID: 10543954

8

Identifying small RNAs derived from maternal- and somatic-type rRNAs in zebrafish development.

Locati MD, Pagano JFB, Abdullah F, Ensink WA, van Olst M, van Leeuwen S, Nehrdich U, Spaink HP, Rauwerda H, Jonker MJ, Dekker RJ, Breit TM. Locati MD, et al. Among authors: dekker rj. Genome. 2018 May;61(5):371-378. doi: 10.1139/gen-2017-0202. Epub 2018 Feb 9. Genome. 2018. PMID: 29425468 Free article.

9

KLF2 provokes a gene expression pattern that establishes functional quiescent differentiation of the endothelium.

Dekker RJ, Boon RA, Rondaij MG, Kragt A, Volger OL, Elderkamp YW, Meijers JC, Voorberg J, Pannekoek H, Horrevoets AJ. Dekker RJ, et al. Blood. 2006 Jun 1;107(11):4354-63. doi: 10.1182/blood-2005-08-3465. Epub 2006 Feb 2. Blood. 2006. PMID: 16455954 Free article.

10

Shear stress sustains atheroprotective endothelial KLF2 expression more potently than statins through mRNA stabilization.

van Thienen JV, Fledderus JO, Dekker RJ, Rohlena J, van Ijzendoorn GA, Kootstra NA, Pannekoek H, Horrevoets AJ. van Thienen JV, et al. Among authors: dekker rj. Cardiovasc Res. 2006 Nov 1;72(2):231-40. doi: 10.1016/j.cardiores.2006.07.008. Epub 2006 Jul 12. Cardiovasc Res. 2006. PMID: 16945356

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