Gorfe AA - Search Results

1

Oncogenic K-Ras Binds to an Anionic Membrane in Two Distinct Orientations: A Molecular Dynamics Analysis.

Prakash P, Zhou Y, Liang H, Hancock JF, Gorfe AA. Prakash P, et al. Among authors: gorfe aa. Biophys J. 2016 Mar 8;110(5):1125-38. doi: 10.1016/j.bpj.2016.01.019. Biophys J. 2016. PMID: 26958889 Free PMC article.

2

Structure and dynamics of the full-length lipid-modified H-Ras protein in a 1,2-dimyristoylglycero-3-phosphocholine bilayer.

Gorfe AA, Hanzal-Bayer M, Abankwa D, Hancock JF, McCammon JA. Gorfe AA, et al. J Med Chem. 2007 Feb 22;50(4):674-84. doi: 10.1021/jm061053f. Epub 2007 Jan 31. J Med Chem. 2007. PMID: 17263520

3

Ras nanoclusters: molecular structure and assembly.

Abankwa D, Gorfe AA, Hancock JF. Abankwa D, et al. Among authors: gorfe aa. Semin Cell Dev Biol. 2007 Oct;18(5):599-607. doi: 10.1016/j.semcdb.2007.08.003. Epub 2007 Aug 19. Semin Cell Dev Biol. 2007. PMID: 17897845 Free PMC article. Review.

4

A novel switch region regulates H-ras membrane orientation and signal output.

Abankwa D, Hanzal-Bayer M, Ariotti N, Plowman SJ, Gorfe AA, Parton RG, McCammon JA, Hancock JF. Abankwa D, et al. Among authors: gorfe aa. EMBO J. 2008 Mar 5;27(5):727-35. doi: 10.1038/emboj.2008.10. Epub 2008 Feb 14. EMBO J. 2008. PMID: 18273062 Free PMC article.

5

Water-membrane partition thermodynamics of an amphiphilic lipopeptide: an enthalpy-driven hydrophobic effect.

Gorfe AA, Baron R, McCammon JA. Gorfe AA, et al. Biophys J. 2008 Oct;95(7):3269-77. doi: 10.1529/biophysj.108.136481. Epub 2008 Jul 11. Biophys J. 2008. PMID: 18621822 Free PMC article.

6

Mechanisms of Ras membrane organization and signalling: Ras on a rocker.

Abankwa D, Gorfe AA, Hancock JF. Abankwa D, et al. Among authors: gorfe aa. Cell Cycle. 2008 Sep 1;7(17):2667-73. doi: 10.4161/cc.7.17.6596. Epub 2008 Sep 28. Cell Cycle. 2008. PMID: 18758236 Free PMC article.

7

Enzymatic activity versus structural dynamics: the case of acetylcholinesterase tetramer.

Gorfe AA, Lu B, Yu Z, McCammon JA. Gorfe AA, et al. Biophys J. 2009 Aug 5;97(3):897-905. doi: 10.1016/j.bpj.2009.05.033. Biophys J. 2009. PMID: 19651048 Free PMC article.

8

Mechanisms of allostery and membrane attachment in Ras GTPases: implications for anti-cancer drug discovery.

Gorfe AA. Gorfe AA. Curr Med Chem. 2010;17(1):1-9. doi: 10.2174/092986710789957832. Curr Med Chem. 2010. PMID: 19941482 Review.

9

Ras membrane orientation and nanodomain localization generate isoform diversity.

Abankwa D, Gorfe AA, Inder K, Hancock JF. Abankwa D, et al. Among authors: gorfe aa. Proc Natl Acad Sci U S A. 2010 Jan 19;107(3):1130-5. doi: 10.1073/pnas.0903907107. Epub 2010 Jan 4. Proc Natl Acad Sci U S A. 2010. PMID: 20080631 Free PMC article.

10

Importance of the sphingosine base double-bond geometry for the structural and thermodynamic properties of sphingomyelin bilayers.

Janosi L, Gorfe A. Janosi L, et al. Biophys J. 2010 Nov 3;99(9):2957-66. doi: 10.1016/j.bpj.2010.09.020. Biophys J. 2010. PMID: 21044593 Free PMC article.

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