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Atypical profiles and modulations of heme-enzymes catalyzed outcomes by low amounts of diverse additives suggest diffusible radicals' obligatory involvement in such redox reactions.
Manoj KM, Parashar A, Venkatachalam A, Goyal S, Satyalipsu, Singh PG, Gade SK, Periyasami K, Jacob RS, Sardar D, Singh S, Kumar R, Gideon DA. Manoj KM, et al. Among authors: venkatachalam a. Biochimie. 2016 Jun;125:91-111. doi: 10.1016/j.biochi.2016.03.003. Epub 2016 Mar 10. Biochimie. 2016. PMID: 26969799
RESULTS: When the rate of specific product formation was studied as a function of reactants' concentration or environmental conditions, we noted marked deviations from normal profiles. ...At low enzyme and peroxide concentrations, the enzyme is seen to recycle via a …
RESULTS: When the rate of specific product formation was studied as a function of reactants' concentration or environmental condition …
Lysosomal reduced thiols are essential for mouse embryonic development.
Adelmann CH, Venkatachalam A, Huang L, Liu M, Germana S, Sabatini DM, Fisher DE. Adelmann CH, et al. Among authors: venkatachalam a. bioRxiv [Preprint]. 2024 Dec 26:2024.12.26.630348. doi: 10.1101/2024.12.26.630348. bioRxiv. 2024. PMID: 39764028 Free PMC article. Preprint.
Delayed Dissociation and Transient Isomerization during the Ultrafast Photodissociation of the Tribromomethane Cation.
Bhattacharyya S, Wang E, Borne K, Chen K, Venkatachalam AS, Lam HVS, Ziaee F, Pathak S, Khmelnitskiy A, Carnes KD, Fehrenbach CW, Ben-Itzhak I, Rudenko A, Rolles D. Bhattacharyya S, et al. Among authors: venkatachalam as. J Phys Chem Lett. 2024 Dec 12;15(49):12188-12196. doi: 10.1021/acs.jpclett.4c02838. Epub 2024 Dec 2. J Phys Chem Lett. 2024. PMID: 39622006
Phase I First-in-Human Dose Escalation Study of the oral Casein Kinase 1α and Cyclin Dependent Kinase 7/9 inhibitor BTX-A51 in advanced MDS and AML.
Ball B, Xiao W, Borthakur G, Nguyen LXT, Valerio M, Venkatachalam A, Marcucci G, Stein A, Thai DL, Cook D, Chan K, Persaud S, Levine R, Abdel-Wahab O, Ben-Neriah Y, Stein E. Ball B, et al. Among authors: venkatachalam a. Res Sq [Preprint]. 2024 Oct 15:rs.3.rs-4954060. doi: 10.21203/rs.3.rs-4954060/v1. Res Sq. 2024. PMID: 39483885 Free PMC article. Preprint.
Proapoptotic activity of JNK-sensitive BH3-only proteins underpins ovarian cancer response to replication checkpoint inhibitors.
Venkatachalam A, Correia C, Peterson KL, Hou X, Schneider PA, Strathman AR, Flatten KS, Sine CC, Balczewski EA, McGehee CD, Larson MC, Duffield LN, Meng XW, Vincelette ND, Ding H, Oberg AL, Couch FJ, Swisher EM, Li H, Weroha SJ, Kaufmann SH. Venkatachalam A, et al. Mol Cancer. 2024 Oct 7;23(1):224. doi: 10.1186/s12943-024-02125-5. Mol Cancer. 2024. PMID: 39375715 Free PMC article.
Hexagonal vortices enable faster colloidal crystal grain coarsening.
Chaffee HK, Corona-Oceguera E, Couto CG, Anne AN, Rogers EL, Galper AL, Floyd CM, Venkatachalam A, Gerbode SJ. Chaffee HK, et al. Among authors: venkatachalam a. Phys Rev E. 2024 Jul;110(1-1):014608. doi: 10.1103/PhysRevE.110.014608. Phys Rev E. 2024. PMID: 39161012
102 results