Zegarra-Moran O - Search Results

1

Evaluation of a systems biology approach to identify pharmacological correctors of the mutant CFTR chloride channel.

Pesce E, Gorrieri G, Sirci F, Napolitano F, Carrella D, Caci E, Tomati V, Zegarra-Moran O, di Bernardo D, Galietta LJ. Pesce E, et al. Among authors: zegarra moran o. J Cyst Fibros. 2016 Jul;15(4):425-35. doi: 10.1016/j.jcf.2016.02.009. Epub 2016 Mar 10. J Cyst Fibros. 2016. PMID: 26971626 Free article.

2

Antihypertensive 1,4-dihydropyridines as correctors of the cystic fibrosis transmembrane conductance regulator channel gating defect caused by cystic fibrosis mutations.

Pedemonte N, Diena T, Caci E, Nieddu E, Mazzei M, Ravazzolo R, Zegarra-Moran O, Galietta LJ. Pedemonte N, et al. Mol Pharmacol. 2005 Dec;68(6):1736-46. doi: 10.1124/mol.105.015149. Epub 2005 Sep 8. Mol Pharmacol. 2005. PMID: 16150931

3

Block of CFTR-dependent chloride currents by inhibitors of multidrug resistance-associated proteins.

Diena T, Melani R, Caci E, Pedemonte N, Sondo E, Zegarra-Moran O, Galietta LJ. Diena T, et al. Eur J Pharmacol. 2007 Apr 10;560(2-3):127-31. doi: 10.1016/j.ejphar.2007.01.051. Epub 2007 Feb 3. Eur J Pharmacol. 2007. PMID: 17320853 Free PMC article.

4

Dual activity of aminoarylthiazoles on the trafficking and gating defects of the cystic fibrosis transmembrane conductance regulator chloride channel caused by cystic fibrosis mutations.

Pedemonte N, Tomati V, Sondo E, Caci E, Millo E, Armirotti A, Damonte G, Zegarra-Moran O, Galietta LJ. Pedemonte N, et al. J Biol Chem. 2011 Apr 29;286(17):15215-26. doi: 10.1074/jbc.M110.184267. Epub 2011 Mar 7. J Biol Chem. 2011. PMID: 21383017 Free PMC article.

5

High-throughput screening of libraries of compounds to identify CFTR modulators.

Pedemonte N, Zegarra-Moran O, Galietta LJ. Pedemonte N, et al. Methods Mol Biol. 2011;741:13-21. doi: 10.1007/978-1-61779-117-8_2. Methods Mol Biol. 2011. PMID: 21594775

6

Synthesis and structure-activity relationship of aminoarylthiazole derivatives as correctors of the chloride transport defect in cystic fibrosis.

Pesce E, Bellotti M, Liessi N, Guariento S, Damonte G, Cichero E, Galatini A, Salis A, Gianotti A, Pedemonte N, Zegarra-Moran O, Fossa P, Galietta LJ, Millo E. Pesce E, et al. Among authors: zegarra moran o. Eur J Med Chem. 2015 Jun 24;99:14-35. doi: 10.1016/j.ejmech.2015.05.030. Epub 2015 May 28. Eur J Med Chem. 2015. PMID: 26041577

7

Pharmacological rescue of mutant CFTR protein improves the viscoelastic properties of CF mucus.

Gianotti A, Capurro V, Scudieri P, Galietta LJ, Moran O, Zegarra-Moran O. Gianotti A, et al. Among authors: zegarra moran o. J Cyst Fibros. 2016 May;15(3):295-301. doi: 10.1016/j.jcf.2015.11.003. Epub 2015 Dec 9. J Cyst Fibros. 2016. PMID: 26677762 Free article.

8

Pharmacological analysis of epithelial chloride secretion mechanisms in adult murine airways.

Gianotti A, Ferrera L, Philp AR, Caci E, Zegarra-Moran O, Galietta LJ, Flores CA. Gianotti A, et al. Among authors: zegarra moran o. Eur J Pharmacol. 2016 Jun 15;781:100-8. doi: 10.1016/j.ejphar.2016.04.007. Epub 2016 Apr 7. Eur J Pharmacol. 2016. PMID: 27063443

9

CFTR pharmacology.

Zegarra-Moran O, Galietta LJ. Zegarra-Moran O, et al. Cell Mol Life Sci. 2017 Jan;74(1):117-128. doi: 10.1007/s00018-016-2392-x. Epub 2016 Oct 4. Cell Mol Life Sci. 2017. PMID: 27704174 Free PMC article. Review.

10

IL-4 is a potent modulator of ion transport in the human bronchial epithelium in vitro.

Galietta LJ, Pagesy P, Folli C, Caci E, Romio L, Costes B, Nicolis E, Cabrini G, Goossens M, Ravazzolo R, Zegarra-Moran O. Galietta LJ, et al. J Immunol. 2002 Jan 15;168(2):839-45. doi: 10.4049/jimmunol.168.2.839. J Immunol. 2002. PMID: 11777980

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