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Page 1
Design, Synthesis, and Biological Evaluation of Imidazo[1,5-a]quinoline as Highly Potent Ligands of Central Benzodiazepine Receptors.
Cappelli A, Anzini M, Castriconi F, Grisci G, Paolino M, Braile C, Valenti S, Giuliani G, Vomero S, Di Capua A, Betti L, Giannaccini G, Lucacchini A, Ghelardini C, Di Cesare Mannelli L, Frosini M, Ricci L, Giorgi G, Mascia MP, Biggio G. Cappelli A, et al. Among authors: biggio g. J Med Chem. 2016 Apr 14;59(7):3353-72. doi: 10.1021/acs.jmedchem.6b00034. Epub 2016 Mar 24. J Med Chem. 2016. PMID: 26982523
New insight into the central benzodiazepine receptor-ligand interactions: design, synthesis, biological evaluation, and molecular modeling of 3-substituted 6-phenyl-4H-imidazo[1,5-a][1,4]benzodiazepines and related compounds.
Anzini M, Valenti S, Braile C, Cappelli A, Vomero S, Alcaro S, Ortuso F, Marinelli L, Limongelli V, Novellino E, Betti L, Giannaccini G, Lucacchini A, Daniele S, Martini C, Ghelardini C, Di Cesare Mannelli L, Giorgi G, Mascia MP, Biggio G. Anzini M, et al. Among authors: biggio g. J Med Chem. 2011 Aug 25;54(16):5694-711. doi: 10.1021/jm2001597. Epub 2011 Jul 27. J Med Chem. 2011. PMID: 21751815
Synthesis and structure-activity relationship studies in translocator protein ligands based on a pyrazolo[3,4-b]quinoline scaffold.
Cappelli A, Bini G, Valenti S, Giuliani G, Paolino M, Anzini M, Vomero S, Giorgi G, Giordani A, Stasi LP, Makovec F, Ghelardini C, Di Cesare Mannelli L, Concas A, Porcu P, Biggio G. Cappelli A, et al. Among authors: biggio g. J Med Chem. 2011 Oct 27;54(20):7165-75. doi: 10.1021/jm200770f. Epub 2011 Sep 26. J Med Chem. 2011. PMID: 21916402
High affinity central benzodiazepine receptor ligands. Part 3: insights into the pharmacophore and pattern recognition study of intrinsic activities of pyrazolo[4,3-c]quinolin-3-ones.
Carotti A, Altomare C, Savini L, Chiasserini L, Pellerano C, Mascia MP, Maciocco E, Busonero F, Mameli M, Biggio G, Sanna E. Carotti A, et al. Among authors: biggio g. Bioorg Med Chem. 2003 Nov 17;11(23):5259-72. doi: 10.1016/s0968-0896(03)00527-3. Bioorg Med Chem. 2003. PMID: 14604690
Carborane-conjugated 2-quinolinecarboxamide ligands of the translocator protein for boron neutron capture therapy.
Cappelli A, Valenti S, Mancini A, Giuliani G, Anzini M, Altieri S, Bortolussi S, Ferrari C, Clerici AM, Zonta C, Carraro F, Filippi I, Giorgi G, Donati A, Ristori S, Vomero S, Concas A, Biggio G. Cappelli A, et al. Among authors: biggio g. Bioconjug Chem. 2010 Dec 15;21(12):2213-21. doi: 10.1021/bc100195s. Epub 2010 Nov 18. Bioconjug Chem. 2010. PMID: 21087014
374 results