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Page 1
Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis.
Sharma R, Al Jayoussi G, Tyrer HE, Gamble J, Hayward L, Guimaraes AF, Davies J, Waterhouse D, Cook DA, Myhill LJ, Clare RH, Cassidy A, Steven A, Johnston KL, Ford L, Turner JD, Ward SA, Taylor MJ. Sharma R, et al. Among authors: myhill lj. Sci Rep. 2016 Mar 21;6:23458. doi: 10.1038/srep23458. Sci Rep. 2016. PMID: 26996237 Free PMC article.
Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis.
Aljayyoussi G, Tyrer HE, Ford L, Sjoberg H, Pionnier N, Waterhouse D, Davies J, Gamble J, Metuge H, Cook DAN, Steven A, Sharma R, Guimaraes AF, Clare RH, Cassidy A, Johnston KL, Myhill L, Hayward L, Wanji S, Turner JD, Taylor MJ, Ward SA. Aljayyoussi G, et al. Sci Rep. 2017 Mar 16;7(1):210. doi: 10.1038/s41598-017-00322-5. Sci Rep. 2017. PMID: 28303006 Free PMC article.
Author Correction: Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis.
Aljayyoussi G, Tyrer HE, Ford L, Sjoberg H, Pionnier N, Waterhouse D, Davies J, Gamble J, Metuge H, Cook DAN, Steven A, Sharma R, Guimaraes AF, Clare RH, Cassidy A, Johnston KL, Myhill L, Hayward L, Wanji S, Turner JD, Taylor MJ, Ward SA. Aljayyoussi G, et al. Sci Rep. 2018 Jan 18;8(1):1384. doi: 10.1038/s41598-018-19723-1. Sci Rep. 2018. PMID: 29348597 Free PMC article.
Boron-Pleuromutilins as Anti- Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis.
Jacobs RT, Lunde CS, Freund YR, Hernandez V, Li X, Xia Y, Carter DS, Berry PW, Halladay J, Rock F, Stefanakis R, Easom E, Plattner JJ, Ford L, Johnston KL, Cook DAN, Clare R, Cassidy A, Myhill L, Tyrer H, Gamble J, Guimaraes AF, Steven A, Lenz F, Ehrens A, Frohberger SJ, Koschel M, Hoerauf A, Hübner MP, McNamara CW, Bakowski MA, Turner JD, Taylor MJ, Ward SA. Jacobs RT, et al. J Med Chem. 2019 Mar 14;62(5):2521-2540. doi: 10.1021/acs.jmedchem.8b01854. Epub 2019 Feb 26. J Med Chem. 2019. PMID: 30730745 Free PMC article.
Corrigendum: Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis.
Sharma R, Aljayyoussi G, Tyrer HE, Gamble J, Hayward L, Guimaraes AF, Davies J, Waterhouse D, Cook DAN, Myhill LJ, Clare RH, Cassidy A, Steven A, Johnston KL, Ford L, Turner JD, Ward SA, Taylor MJ. Sharma R, et al. Among authors: myhill lj. Sci Rep. 2018 Jan 8;8:46934. doi: 10.1038/srep46934. Sci Rep. 2018. PMID: 29308790 Free PMC article.
Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides.
Clare RH, Bardelle C, Harper P, Hong WD, Börjesson U, Johnston KL, Collier M, Myhill L, Cassidy A, Plant D, Plant H, Clark R, Cook DAN, Steven A, Archer J, McGillan P, Charoensutthivarakul S, Bibby J, Sharma R, Nixon GL, Slatko BE, Cantin L, Wu B, Turner J, Ford L, Rich K, Wigglesworth M, Berry NG, O'Neill PM, Taylor MJ, Ward SA. Clare RH, et al. Nat Commun. 2019 Jan 2;10(1):11. doi: 10.1038/s41467-018-07826-2. Nat Commun. 2019. PMID: 30602718 Free PMC article.
Gut microbiota-mediated polyphenol metabolism is restrained by parasitic whipworm infection and associated with altered immune function in mice.
Schytz Andersen-Civil AI, Arora P, Zhu L, Myhill LJ, Büdeyri Gökgöz N, Castro-Mejia JL, Leppä MM, Hansen LH, Lessard-Lord J, Salminen JP, Thamsborg SM, Sandris Nielsen D, Desjardins Y, Williams AR. Schytz Andersen-Civil AI, et al. Among authors: myhill lj. Gut Microbes. 2024 Jan-Dec;16(1):2370917. doi: 10.1080/19490976.2024.2370917. Epub 2024 Jun 30. Gut Microbes. 2024. PMID: 38944838 Free PMC article.
Diet composition drives tissue-specific intensity of murine enteric infections.
Israelson H, Vedsted-Jakobsen A, Zhu L, Gagnaire A, von Münchow A, Polakovicova N, Valente AH, Raza A, Andersen-Civil AIS, Olsen JE, Myhill LJ, Geldhof P, Williams AR. Israelson H, et al. Among authors: myhill lj. mBio. 2024 Feb 14;15(2):e0260323. doi: 10.1128/mbio.02603-23. Epub 2024 Jan 5. mBio. 2024. PMID: 38179939 Free PMC article.
Dietary seaweed (Saccharina latissima) supplementation in pigs induces localized immunomodulatory effects and minor gut microbiota changes during intestinal helminth infection.
Bonde CS, Mejer H, Myhill LJ, Zhu L, Jensen P, Büdeyri Gökgöz N, Krych L, Nielsen DS, Skovgaard K, Thamsborg SM, Williams AR. Bonde CS, et al. Among authors: myhill lj. Sci Rep. 2023 Dec 11;13(1):21931. doi: 10.1038/s41598-023-49082-5. Sci Rep. 2023. PMID: 38081984 Free PMC article.
Dietary non-starch polysaccharides impair immunity to enteric nematode infection.
Valente AH, Jensen KMR, Myhill LJ, Zhu L, Mentzel CMJ, Krych L, Simonsen HT, Castro-Mejía JL, Gobbi A, Bach Knudsen KE, Nielsen DS, Thamsborg SM, Williams AR. Valente AH, et al. Among authors: myhill lj. BMC Biol. 2023 Jun 14;21(1):138. doi: 10.1186/s12915-023-01640-z. BMC Biol. 2023. PMID: 37316905 Free PMC article.
23 results