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Targeting the 19S proteasomal subunit, Rpt4, for the treatment of colon cancer.
Boland K, Flanagan L, McCawley N, Pabari R, Kay EW, McNamara DA, Murray F, Byrne AT, Ramtoola Z, Concannon CG, Prehn JH. Boland K, et al. Among authors: byrne at. Eur J Pharmacol. 2016 Jun 5;780:53-64. doi: 10.1016/j.ejphar.2016.03.031. Epub 2016 Mar 17. Eur J Pharmacol. 2016. PMID: 26997367
Patient-derived glioblastoma cells show significant heterogeneity in treatment responses to the inhibitor-of-apoptosis-protein antagonist birinapant.
Zakaria Z, Tivnan A, Flanagan L, Murray DW, Salvucci M, Stringer BW, Day BW, Boyd AW, Kögel D, Rehm M, O'Brien DF, Byrne AT, Prehn JH. Zakaria Z, et al. Among authors: byrne at. Br J Cancer. 2016 Jan 19;114(2):188-98. doi: 10.1038/bjc.2015.420. Epub 2015 Dec 10. Br J Cancer. 2016. PMID: 26657652 Free PMC article.
Mechanistic interrogation of combination bevacizumab/dual PI3K/mTOR inhibitor response in glioblastoma implementing novel MR and PET imaging biomarkers.
O'Halloran PJ, Viel T, Murray DW, Wachsmuth L, Schwegmann K, Wagner S, Kopka K, Jarzabek MA, Dicker P, Hermann S, Faber C, Klasen T, Schäfers M, O'Brien D, Prehn JH, Jacobs AH, Byrne AT. O'Halloran PJ, et al. Among authors: byrne at. Eur J Nucl Med Mol Imaging. 2016 Aug;43(9):1673-83. doi: 10.1007/s00259-016-3343-3. Epub 2016 Mar 15. Eur J Nucl Med Mol Imaging. 2016. PMID: 26975402
Outcome of Colorectal Cancer Patients Treated with Combination Bevacizumab Therapy: A Pooled Retrospective Analysis of Three European Cohorts from the Angiopredict Initiative.
Betge J, Barat A, Murphy V, Hielscher T, Van Grieken NC, Belle S, Zhan T, Härtel N, Kripp M, Bacon O, Cordes M, Kay EW, Verheul HM, Neerincx M, Hennessy B, Hofheinz RD, Gaiser T, Ylstra B, Prehn JH, Lambrechts D, Byrne AT, Ebert MP, Schulte N. Betge J, et al. Among authors: byrne at. Digestion. 2016;94(3):129-137. doi: 10.1159/000449412. Epub 2016 Oct 19. Digestion. 2016. PMID: 27756074
102 results