Dubyak GR - Search Results

1

T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis.

Martin BN, Wang C, Zhang CJ, Kang Z, Gulen MF, Zepp JA, Zhao J, Bian G, Do JS, Min B, Pavicic PG Jr, El-Sanadi C, Fox PL, Akitsu A, Iwakura Y, Sarkar A, Wewers MD, Kaiser WJ, Mocarski ES, Rothenberg ME, Hise AG, Dubyak GR, Ransohoff RM, Li X. Martin BN, et al. Among authors: dubyak gr. Nat Immunol. 2016 May;17(5):583-92. doi: 10.1038/ni.3389. Epub 2016 Mar 21. Nat Immunol. 2016. PMID: 26998763 Free PMC article.

2

Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages.

Qu Y, Franchi L, Nunez G, Dubyak GR. Qu Y, et al. Among authors: dubyak gr. J Immunol. 2007 Aug 1;179(3):1913-25. doi: 10.4049/jimmunol.179.3.1913. J Immunol. 2007. PMID: 17641058

3

P2X7 receptor-stimulated secretion of MHC class II-containing exosomes requires the ASC/NLRP3 inflammasome but is independent of caspase-1.

Qu Y, Ramachandra L, Mohr S, Franchi L, Harding CV, Nunez G, Dubyak GR. Qu Y, et al. Among authors: dubyak gr. J Immunol. 2009 Apr 15;182(8):5052-62. doi: 10.4049/jimmunol.0802968. J Immunol. 2009. PMID: 19342685 Free PMC article.

4

Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1β via caspase-8 in dendritic cells.

Antonopoulos C, El Sanadi C, Kaiser WJ, Mocarski ES, Dubyak GR. Antonopoulos C, et al. Among authors: dubyak gr. J Immunol. 2013 Nov 1;191(9):4789-803. doi: 10.4049/jimmunol.1300645. Epub 2013 Sep 27. J Immunol. 2013. PMID: 24078693 Free PMC article.

5

IKKα negatively regulates ASC-dependent inflammasome activation.

Martin BN, Wang C, Willette-Brown J, Herjan T, Gulen MF, Zhou H, Bulek K, Franchi L, Sato T, Alnemri ES, Narla G, Zhong XP, Thomas J, Klinman D, Fitzgerald KA, Karin M, Nuñez G, Dubyak G, Hu Y, Li X. Martin BN, et al. Nat Commun. 2014 Sep 30;5:4977. doi: 10.1038/ncomms5977. Nat Commun. 2014. PMID: 25266676 Free PMC article.

6

Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux.

Karmakar M, Katsnelson M, Malak HA, Greene NG, Howell SJ, Hise AG, Camilli A, Kadioglu A, Dubyak GR, Pearlman E. Karmakar M, et al. Among authors: dubyak gr. J Immunol. 2015 Feb 15;194(4):1763-75. doi: 10.4049/jimmunol.1401624. Epub 2015 Jan 21. J Immunol. 2015. PMID: 25609842 Free PMC article.

7

K+ efflux agonists induce NLRP3 inflammasome activation independently of Ca2+ signaling.

Katsnelson MA, Rucker LG, Russo HM, Dubyak GR. Katsnelson MA, et al. Among authors: dubyak gr. J Immunol. 2015 Apr 15;194(8):3937-52. doi: 10.4049/jimmunol.1402658. Epub 2015 Mar 11. J Immunol. 2015. PMID: 25762778 Free PMC article.

8

Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling.

Antonopoulos C, Russo HM, El Sanadi C, Martin BN, Li X, Kaiser WJ, Mocarski ES, Dubyak GR. Antonopoulos C, et al. Among authors: dubyak gr. J Biol Chem. 2015 Aug 14;290(33):20167-84. doi: 10.1074/jbc.M115.652321. Epub 2015 Jun 22. J Biol Chem. 2015. PMID: 26100631 Free PMC article.

9

Modification of β-Defensin-2 by Dicarbonyls Methylglyoxal and Glyoxal Inhibits Antibacterial and Chemotactic Function In Vitro.

Kiselar JG, Wang X, Dubyak GR, El Sanadi C, Ghosh SK, Lundberg K, Williams WM. Kiselar JG, et al. Among authors: dubyak gr. PLoS One. 2015 Aug 5;10(8):e0130533. doi: 10.1371/journal.pone.0130533. eCollection 2015. PLoS One. 2015. PMID: 26244639 Free PMC article.

10

Human β Defensin-3 Increases CD86 Expression on Monocytes by Activating the ATP-Gated Channel P2X7.

Lioi AB, Ferrari BM, Dubyak GR, Weinberg A, Sieg SF. Lioi AB, et al. Among authors: dubyak gr. J Immunol. 2015 Nov 1;195(9):4438-45. doi: 10.4049/jimmunol.1401319. Epub 2015 Sep 28. J Immunol. 2015. PMID: 26416278 Free PMC article.

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