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Prognostic and therapeutic relevance of molecular subtypes in high-grade serous ovarian cancer.
Konecny GE, Wang C, Hamidi H, Winterhoff B, Kalli KR, Dering J, Ginther C, Chen HW, Dowdy S, Cliby W, Gostout B, Podratz KC, Keeney G, Wang HJ, Hartmann LC, Slamon DJ, Goode EL. Konecny GE, et al. Among authors: chen hw. J Natl Cancer Inst. 2014 Sep 30;106(10):dju249. doi: 10.1093/jnci/dju249. Print 2014 Oct. J Natl Cancer Inst. 2014. PMID: 25269487 Free PMC article.
Expression signature distinguishing two tumour transcriptome classes associated with progression-free survival among rare histological types of epithelial ovarian cancer.
Wang C, Winterhoff BJ, Kalli KR, Block MS, Armasu SM, Larson MC, Chen HW, Keeney GL, Hartmann LC, Shridhar V, Konecny GE, Goode EL, Fridley BL. Wang C, et al. Among authors: chen hw. Br J Cancer. 2016 Jun 14;114(12):1412-20. doi: 10.1038/bjc.2016.124. Epub 2016 Jun 2. Br J Cancer. 2016. PMID: 27253175 Free PMC article.
Results of TRIO-14, a phase II, multicenter, randomized, placebo-controlled trial of carboplatin-paclitaxel versus carboplatin-paclitaxel-ganitumab in newly diagnosed epithelial ovarian cancer.
Konecny GE, Hendrickson AEW, Davidson TM, Winterhoff BJ, Ma S, Mahner S, Sehouli J, Fasching PA, Feisel-Schwickardi G, Poelcher M, Roman LD, Rody A, Karlan BY, Mullany SA, Chen H, Ray-Coquard IL, Provencher DM, Yachnin A, Cottu PH, Glaspy JA, Haluska P, Slamon DJ. Konecny GE, et al. Gynecol Oncol. 2021 Dec;163(3):465-472. doi: 10.1016/j.ygyno.2021.09.025. Epub 2021 Oct 9. Gynecol Oncol. 2021. PMID: 34642026 Free article. Clinical Trial.
PD-0332991, a potent and selective inhibitor of cyclin-dependent kinase 4/6, demonstrates inhibition of proliferation in renal cell carcinoma at nanomolar concentrations and molecular markers predict for sensitivity.
Logan JE, Mostofizadeh N, Desai AJ, VON Euw E, Conklin D, Konkankit V, Hamidi H, Eckardt M, Anderson L, Chen HW, Ginther C, Taschereau E, Bui PH, Christensen JG, Belldegrun AS, Slamon DJ, Kabbinavar FF. Logan JE, et al. Among authors: chen hw. Anticancer Res. 2013 Aug;33(8):2997-3004. Anticancer Res. 2013. PMID: 23898052
Pathologic and molecular responses to neoadjuvant trastuzumab and/or lapatinib from a phase II randomized trial in HER2-positive breast cancer (TRIO-US B07).
Hurvitz SA, Caswell-Jin JL, McNamara KL, Zoeller JJ, Bean GR, Dichmann R, Perez A, Patel R, Zehngebot L, Allen H, Bosserman L, DiCarlo B, Kennedy A, Giuliano A, Calfa C, Molthrop D, Mani A, Chen HW, Dering J, Adams B, Kotler E, Press MF, Brugge JS, Curtis C, Slamon DJ. Hurvitz SA, et al. Among authors: chen hw. Nat Commun. 2020 Nov 17;11(1):5824. doi: 10.1038/s41467-020-19494-2. Nat Commun. 2020. PMID: 33203854 Free PMC article. Clinical Trial.
1,725 results