Knudsen BR - Search Results

1

Synthesis and biological evaluation of indeno[1,5]naphthyridines as topoisomerase I (TopI) inhibitors with antiproliferative activity.

Alonso C, Fuertes M, González M, Rubiales G, Tesauro C, Knudsen BR, Palacios F. Alonso C, et al. Among authors: knudsen br. Eur J Med Chem. 2016 Jun 10;115:179-90. doi: 10.1016/j.ejmech.2016.03.031. Epub 2016 Mar 14. Eur J Med Chem. 2016. PMID: 27017547

2

Dissecting the cell-killing mechanism of the topoisomerase II-targeting drug ICRF-193.

Oestergaard VH, Knudsen BR, Andersen AH. Oestergaard VH, et al. Among authors: knudsen br. J Biol Chem. 2004 Jul 2;279(27):28100-5. doi: 10.1074/jbc.M402119200. Epub 2004 Apr 28. J Biol Chem. 2004. PMID: 15123716 Free article.

3

Specific detection of topoisomerase I from the malaria causing P. falciparum parasite using isothermal rolling circle amplification.

Tesauro C, Juul S, Arnò B, Nielsen CJ, Fiorani P, Frøhlich RF, Andersen FF, Desideri A, Stougaard M, Petersen E, Knudsen BR. Tesauro C, et al. Among authors: knudsen br. Annu Int Conf IEEE Eng Med Biol Soc. 2012;2012:2416-9. doi: 10.1109/EMBC.2012.6346451. Annu Int Conf IEEE Eng Med Biol Soc. 2012. PMID: 23366412

4

Replacement of the human topoisomerase linker domain with the plasmodial counterpart renders the enzyme camptothecin resistant.

Arnò B, D'Annessa I, Tesauro C, Zuccaro L, Ottaviani A, Knudsen B, Fiorani P, Desideri A. Arnò B, et al. PLoS One. 2013 Jul 2;8(7):e68404. doi: 10.1371/journal.pone.0068404. Print 2013. PLoS One. 2013. PMID: 23844196 Free PMC article.

5

Rolling circle amplification-based detection of human topoisomerase I activity on magnetic beads.

Zuccaro L, Tesauro C, Cerroni B, Ottaviani A, Knudsen BR, Balasubramanian K, Desideri A. Zuccaro L, et al. Among authors: knudsen br. Anal Biochem. 2014 Apr 15;451:42-4. doi: 10.1016/j.ab.2014.02.003. Epub 2014 Feb 11. Anal Biochem. 2014. PMID: 24525043

6

Decreased camptothecin sensitivity of the stem-cell-like fraction of Caco2 cells correlates with an altered phosphorylation pattern of topoisomerase I.

Roy A, Tesauro C, Frøhlich R, Hede MS, Nielsen MJ, Kjeldsen E, Bonven B, Stougaard M, Gromova I, Knudsen BR. Roy A, et al. Among authors: knudsen br. PLoS One. 2014 Jun 24;9(6):e99628. doi: 10.1371/journal.pone.0099628. eCollection 2014. PLoS One. 2014. PMID: 24960044 Free PMC article.

7

Real-Time Label-Free Direct Electronic Monitoring of Topoisomerase Enzyme Binding Kinetics on Graphene.

Zuccaro L, Tesauro C, Kurkina T, Fiorani P, Yu HK, Knudsen BR, Kern K, Desideri A, Balasubramanian K. Zuccaro L, et al. Among authors: knudsen br. ACS Nano. 2015 Nov 24;9(11):11166-76. doi: 10.1021/acsnano.5b05709. Epub 2015 Oct 12. ACS Nano. 2015. PMID: 26445172

8

Microfluidics-Enabled Enzyme Activity Measurement in Single Cells.

Tesauro C, Frøhlich R, Stougaard M, Ho YP, Knudsen BR. Tesauro C, et al. Among authors: knudsen br. Methods Mol Biol. 2015;1346:209-19. doi: 10.1007/978-1-4939-2987-0_14. Methods Mol Biol. 2015. PMID: 26542724

9

Advantages of an optical nanosensor system for the mechanistic analysis of a novel topoisomerase I targeting drug: a case study.

Andersen MB, Tesauro C, Gonzalez M, Kristoffersen EL, Alonso C, Rubiales G, Coletta A, Frøhlich R, Stougaard M, Ho YP, Palacios F, Knudsen BR. Andersen MB, et al. Among authors: knudsen br. Nanoscale. 2017 Feb 2;9(5):1886-1895. doi: 10.1039/c6nr06848k. Nanoscale. 2017. PMID: 28094391

10

On-slide detection of enzymatic activities in selected single cells.

Keller JG, Tesauro C, Coletta A, Graversen AD, Ho YP, Kristensen P, Stougaard M, Knudsen BR. Keller JG, et al. Among authors: knudsen br. Nanoscale. 2017 Sep 21;9(36):13546-13553. doi: 10.1039/c7nr05125e. Nanoscale. 2017. PMID: 28872165

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