Smith DA - Search Results

1

Defective Cytochrome P450-Catalysed Drug Metabolism in Niemann-Pick Type C Disease.

Nicoli ER, Al Eisa N, Cluzeau CV, Wassif CA, Gray J, Burkert KR, Smith DA, Morris L, Cologna SM, Peer CJ, Sissung TM, Uscatu CD, Figg WD, Pavan WJ, Vite CH, Porter FD, Platt FM. Nicoli ER, et al. Among authors: smith da. PLoS One. 2016 Mar 28;11(3):e0152007. doi: 10.1371/journal.pone.0152007. eCollection 2016. PLoS One. 2016. PMID: 27019000 Free PMC article.

2

An inducible mouse model of late onset Tay-Sachs disease.

Jeyakumar M, Smith D, Eliott-Smith E, Cortina-Borja M, Reinkensmeier G, Butters TD, Lemm T, Sandhoff K, Perry VH, Dwek RA, Platt FM. Jeyakumar M, et al. Neurobiol Dis. 2002 Aug;10(3):201-10. doi: 10.1006/nbdi.2002.0511. Neurobiol Dis. 2002. PMID: 12270683

3

Improved outcome of N-butyldeoxygalactonojirimycin-mediated substrate reduction therapy in a mouse model of Sandhoff disease.

Andersson U, Smith D, Jeyakumar M, Butters TD, Borja MC, Dwek RA, Platt FM. Andersson U, et al. Neurobiol Dis. 2004 Aug;16(3):506-15. doi: 10.1016/j.nbd.2004.04.012. Neurobiol Dis. 2004. PMID: 15262262

4

NSAIDs increase survival in the Sandhoff disease mouse: synergy with N-butyldeoxynojirimycin.

Jeyakumar M, Smith DA, Williams IM, Borja MC, Neville DC, Butters TD, Dwek RA, Platt FM. Jeyakumar M, et al. Among authors: smith da. Ann Neurol. 2004 Nov;56(5):642-9. doi: 10.1002/ana.20242. Ann Neurol. 2004. PMID: 15505823

5

Beneficial effects of substrate reduction therapy in a mouse model of GM1 gangliosidosis.

Elliot-Smith E, Speak AO, Lloyd-Evans E, Smith DA, van der Spoel AC, Jeyakumar M, Butters TD, Dwek RA, d'Azzo A, Platt FM. Elliot-Smith E, et al. Among authors: smith da. Mol Genet Metab. 2008 Jun;94(2):204-11. doi: 10.1016/j.ymgme.2008.02.005. Epub 2008 Apr 1. Mol Genet Metab. 2008. PMID: 18387328

6

Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium.

Lloyd-Evans E, Morgan AJ, He X, Smith DA, Elliot-Smith E, Sillence DJ, Churchill GC, Schuchman EH, Galione A, Platt FM. Lloyd-Evans E, et al. Among authors: smith da. Nat Med. 2008 Nov;14(11):1247-55. doi: 10.1038/nm.1876. Epub 2008 Oct 26. Nat Med. 2008. PMID: 18953351

7

Critical role of iron in the pathogenesis of the murine gangliosidoses.

Jeyakumar M, Williams I, Smith D, Cox TM, Platt FM. Jeyakumar M, et al. Neurobiol Dis. 2009 Jun;34(3):406-16. doi: 10.1016/j.nbd.2009.01.015. Neurobiol Dis. 2009. PMID: 19449457

8

Neural stem cell transplantation benefits a monogenic neurometabolic disorder during the symptomatic phase of disease.

Jeyakumar M, Lee JP, Sibson NR, Lowe JP, Stuckey DJ, Tester K, Fu G, Newlin R, Smith DA, Snyder EY, Platt FM. Jeyakumar M, et al. Among authors: smith da. Stem Cells. 2009 Sep;27(9):2362-70. doi: 10.1002/stem.163. Stem Cells. 2009. PMID: 19591217 Free PMC article.

9

Beneficial effects of anti-inflammatory therapy in a mouse model of Niemann-Pick disease type C1.

Smith D, Wallom KL, Williams IM, Jeyakumar M, Platt FM. Smith D, et al. Neurobiol Dis. 2009 Nov;36(2):242-51. doi: 10.1016/j.nbd.2009.07.010. Epub 2009 Jul 24. Neurobiol Dis. 2009. PMID: 19632328

10

Macroautophagy is not directly involved in the metabolism of amyloid precursor protein.

Boland B, Smith DA, Mooney D, Jung SS, Walsh DM, Platt FM. Boland B, et al. Among authors: smith da. J Biol Chem. 2010 Nov 26;285(48):37415-26. doi: 10.1074/jbc.M110.186411. Epub 2010 Sep 23. J Biol Chem. 2010. PMID: 20864542 Free PMC article.

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