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Page 1
Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis.
Mehta AR, Gregory JM, Dando O, Carter RN, Burr K, Nanda J, Story D, McDade K, Smith C, Morton NM, Mahad DJ, Hardingham GE, Chandran S, Selvaraj BT. Mehta AR, et al. Among authors: selvaraj bt. Acta Neuropathol. 2021 Feb;141(2):257-279. doi: 10.1007/s00401-020-02252-5. Epub 2021 Jan 4. Acta Neuropathol. 2021. PMID: 33398403 Free PMC article.
A 3D cell culture system for bioengineering human neuromuscular junctions to model ALS.
Massih B, Veh A, Schenke M, Mungwa S, Seeger B, Selvaraj BT, Chandran S, Reinhardt P, Sterneckert J, Hermann A, Sendtner M, Lüningschrör P. Massih B, et al. Among authors: selvaraj bt. Front Cell Dev Biol. 2023 Feb 14;11:996952. doi: 10.3389/fcell.2023.996952. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 36866276 Free PMC article.
Plekhg5 controls the unconventional secretion of Sod1 by presynaptic secretory autophagy.
Hutchings AJ, Hambrecht B, Veh A, Giridhar NJ, Zare A, Angerer C, Ohnesorge T, Schenke M, Selvaraj BT, Chandran S, Sterneckert J, Petri S, Seeger B, Briese M, Stigloher C, Bischler T, Hermann A, Damme M, Sendtner M, Lüningschrör P. Hutchings AJ, et al. Among authors: selvaraj bt. Nat Commun. 2024 Oct 4;15(1):8622. doi: 10.1038/s41467-024-52875-5. Nat Commun. 2024. PMID: 39366938 Free PMC article.
HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS.
Braems E, Bercier V, Van Schoor E, Heeren K, Beckers J, Fumagalli L, Dedeene L, Moisse M, Geudens I, Hersmus N, Mehta AR, Selvaraj BT, Chandran S, Ho R, Thal DR, Van Damme P, Swinnen B, Van Den Bosch L. Braems E, et al. Among authors: selvaraj bt. Acta Neuropathol. 2022 Sep;144(3):465-488. doi: 10.1007/s00401-022-02471-y. Epub 2022 Jul 27. Acta Neuropathol. 2022. PMID: 35895140 Free PMC article.
PolyGA targets the ER stress-adaptive response by impairing GRP75 function at the MAM in C9ORF72-ALS/FTD.
Pilotto F, Schmitz A, Maharjan N, Diab R, Odriozola A, Tripathi P, Yamoah A, Scheidegger O, Oestmann A, Dennys CN, Sinha Ray S, Rodrigo R, Kolb S, Aronica E, Di Santo S, Widmer HR, Charlet-Berguerand N, Selvaraj BT, Chandran S, Meyer K, Zuber B, Goswami A, Weis J, Saxena S. Pilotto F, et al. Among authors: selvaraj bt. Acta Neuropathol. 2022 Nov;144(5):939-966. doi: 10.1007/s00401-022-02494-5. Epub 2022 Sep 19. Acta Neuropathol. 2022. PMID: 36121477 Free PMC article.
37 results