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An optimized single chain TCR scaffold relying on the assembly with the native CD3-complex prevents residual mispairing with endogenous TCRs in human T-cells.
Knies D, Klobuch S, Xue SA, Birtel M, Echchannaoui H, Yildiz O, Omokoko T, Guillaume P, Romero P, Stauss H, Sahin U, Herr W, Theobald M, Thomas S, Voss RH. Knies D, et al. Among authors: voss rh. Oncotarget. 2016 Apr 19;7(16):21199-221. doi: 10.18632/oncotarget.8385. Oncotarget. 2016. PMID: 27028870 Free PMC article.
Designing TCR for cancer immunotherapy.
Voss RH, Kuball J, Theobald M. Voss RH, et al. Methods Mol Med. 2005;109:229-56. doi: 10.1385/1-59259-862-5:229. Methods Mol Med. 2005. PMID: 15585925
34 results