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Cold-Adapted Viral Attenuation (CAVA): Highly Temperature Sensitive Polioviruses as Novel Vaccine Strains for a Next Generation Inactivated Poliovirus Vaccine.
Sanders BP, de Los Rios Oakes I, van Hoek V, Bockstal V, Kamphuis T, Uil TG, Song Y, Cooper G, Crawt LE, Martín J, Zahn R, Lewis J, Wimmer E, Custers JH, Schuitemaker H, Cello J, Edo-Matas D. Sanders BP, et al. Among authors: cello j. PLoS Pathog. 2016 Mar 31;12(3):e1005483. doi: 10.1371/journal.ppat.1005483. eCollection 2016 Mar. PLoS Pathog. 2016. PMID: 27032093 Free PMC article.
Brunenders: a partially attenuated historic poliovirus type I vaccine strain.
Sanders BP, Liu Y, Brandjes A, van Hoek V, de Los Rios Oakes I, Lewis J, Wimmer E, Custers JHHV, Schuitemaker H, Cello J, Edo-Matas D. Sanders BP, et al. Among authors: cello j. J Gen Virol. 2015 Sep;96(9):2614-2622. doi: 10.1099/vir.0.000197. Epub 2015 May 26. J Gen Virol. 2015. PMID: 26018960
Production of high titer attenuated poliovirus strains on the serum-free PER.C6(®) cell culture platform for the generation of safe and affordable next generation IPV.
Sanders BP, Oakes Ide L, van Hoek V, Liu Y, Marissen W, Minor PD, Wimmer E, Schuitemaker H, Custers JH, Macadam A, Cello J, Edo-Matas D. Sanders BP, et al. Among authors: cello j. Vaccine. 2015 Nov 27;33(48):6611-6. doi: 10.1016/j.vaccine.2015.10.091. Epub 2015 Nov 1. Vaccine. 2015. PMID: 26529068
Mutation of a single conserved nucleotide between the cloverleaf and internal ribosome entry site attenuates poliovirus neurovirulence.
De Jesus N, Franco D, Paul A, Wimmer E, Cello J. De Jesus N, et al. Among authors: cello j. J Virol. 2005 Nov;79(22):14235-43. doi: 10.1128/JVI.79.22.14235-14243.2005. J Virol. 2005. PMID: 16254358 Free PMC article.
The chemical synthesis of poliovirus (PV) cDNA combined with the cell-free synthesis of infectious particles yielded virus whose mouse neurovirulence was highly attenuated (J. Cello, A. V. Paul, and E. Wimmer, Science 297:1016-1018, 2002). Compared to the wild-type …
The chemical synthesis of poliovirus (PV) cDNA combined with the cell-free synthesis of infectious particles yielded virus whose mouse neuro …
155 results