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Human germline antibody gene segments encode polyspecific antibodies.
Willis JR, Briney BS, DeLuca SL, Crowe JE Jr, Meiler J. Willis JR, et al. Among authors: meiler j. PLoS Comput Biol. 2013 Apr;9(4):e1003045. doi: 10.1371/journal.pcbi.1003045. Epub 2013 Apr 25. PLoS Comput Biol. 2013. PMID: 23637590 Free PMC article.
Human rotavirus VP6-specific antibodies mediate intracellular neutralization by binding to a quaternary structure in the transcriptional pore.
Aiyegbo MS, Sapparapu G, Spiller BW, Eli IM, Williams DR, Kim R, Lee DE, Liu T, Li S, Woods VL Jr, Nannemann DP, Meiler J, Stewart PL, Crowe JE Jr. Aiyegbo MS, et al. Among authors: meiler j. PLoS One. 2013 May 9;8(5):e61101. doi: 10.1371/journal.pone.0061101. Print 2013. PLoS One. 2013. PMID: 23671563 Free PMC article.
Small-molecule ligand docking into comparative models with Rosetta.
Combs SA, Deluca SL, Deluca SH, Lemmon GH, Nannemann DP, Nguyen ED, Willis JR, Sheehan JH, Meiler J. Combs SA, et al. Among authors: meiler j. Nat Protoc. 2013;8(7):1277-98. doi: 10.1038/nprot.2013.074. Epub 2013 Jun 6. Nat Protoc. 2013. PMID: 23744289 Free PMC article.
Human antibodies that neutralize respiratory droplet transmissible H5N1 influenza viruses.
Thornburg NJ, Nannemann DP, Blum DL, Belser JA, Tumpey TM, Deshpande S, Fritz GA, Sapparapu G, Krause JC, Lee JH, Ward AB, Lee DE, Li S, Winarski KL, Spiller BW, Meiler J, Crowe JE Jr. Thornburg NJ, et al. Among authors: meiler j. J Clin Invest. 2013 Oct;123(10):4405-9. doi: 10.1172/JCI69377. Epub 2013 Sep 3. J Clin Invest. 2013. PMID: 23999429 Free PMC article.
Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth.
Willis JR, Sapparapu G, Murrell S, Julien JP, Singh V, King HG, Xia Y, Pickens JA, LaBranche CC, Slaughter JC, Montefiori DC, Wilson IA, Meiler J, Crowe JE Jr. Willis JR, et al. Among authors: meiler j. J Clin Invest. 2015 Jun;125(6):2523-31. doi: 10.1172/JCI80693. Epub 2015 May 18. J Clin Invest. 2015. PMID: 25985274 Free PMC article.
Structure and mechanism of the phage T4 recombination mediator protein UvsY.
Gajewski S, Waddell MB, Vaithiyalingam S, Nourse A, Li Z, Woetzel N, Alexander N, Meiler J, White SW. Gajewski S, et al. Among authors: meiler j. Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3275-80. doi: 10.1073/pnas.1519154113. Epub 2016 Mar 7. Proc Natl Acad Sci U S A. 2016. PMID: 26951671 Free PMC article.
449 results