Dean JL - Search Results

1

Neutrophil-derived alpha defensins control inflammation by inhibiting macrophage mRNA translation.

Brook M, Tomlinson GH, Miles K, Smith RW, Rossi AG, Hiemstra PS, van 't Wout EF, Dean JL, Gray NK, Lu W, Gray M. Brook M, et al. Among authors: dean jl. Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):4350-5. doi: 10.1073/pnas.1601831113. Epub 2016 Apr 4. Proc Natl Acad Sci U S A. 2016. PMID: 27044108 Free PMC article.

2

p38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes.

Dean JL, Brook M, Clark AR, Saklatvala J. Dean JL, et al. J Biol Chem. 1999 Jan 1;274(1):264-9. doi: 10.1074/jbc.274.1.264. J Biol Chem. 1999. PMID: 9867839 Free article.

3

Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability.

Mahtani KR, Brook M, Dean JL, Sully G, Saklatvala J, Clark AR. Mahtani KR, et al. Among authors: dean jl. Mol Cell Biol. 2001 Oct;21(19):6461-9. doi: 10.1128/MCB.21.9.6461-6469.2001. Mol Cell Biol. 2001. PMID: 11533235 Free PMC article.

4

A p38 MAP kinase inhibitor regulates stability of interleukin-1-induced cyclooxygenase-2 mRNA.

Ridley SH, Dean JL, Sarsfield SJ, Brook M, Clark AR, Saklatvala J. Ridley SH, et al. Among authors: dean jl. FEBS Lett. 1998 Nov 13;439(1-2):75-80. doi: 10.1016/s0014-5793(98)01342-8. FEBS Lett. 1998. PMID: 9849881 Free article.

5

Dominant Suppression of Inflammation via Targeted Mutation of the mRNA Destabilizing Protein Tristetraprolin.

Ross EA, Smallie T, Ding Q, O'Neil JD, Cunliffe HE, Tang T, Rosner DR, Klevernic I, Morrice NA, Monaco C, Cunningham AF, Buckley CD, Saklatvala J, Dean JL, Clark AR. Ross EA, et al. Among authors: dean jl. J Immunol. 2015 Jul 1;195(1):265-76. doi: 10.4049/jimmunol.1402826. Epub 2015 May 22. J Immunol. 2015. PMID: 26002976 Free PMC article.

6

Dual-Specificity Phosphatase 1 and Tristetraprolin Cooperate To Regulate Macrophage Responses to Lipopolysaccharide.

Smallie T, Ross EA, Ammit AJ, Cunliffe HE, Tang T, Rosner DR, Ridley ML, Buckley CD, Saklatvala J, Dean JL, Clark AR. Smallie T, et al. Among authors: dean jl. J Immunol. 2015 Jul 1;195(1):277-88. doi: 10.4049/jimmunol.1402830. Epub 2015 May 27. J Immunol. 2015. PMID: 26019272 Free PMC article.

7

PARP-14 combines with tristetraprolin in the selective posttranscriptional control of macrophage tissue factor expression.

Iqbal MB, Johns M, Cao J, Liu Y, Yu SC, Hyde GD, Laffan MA, Marchese FP, Cho SH, Clark AR, Gavins FN, Woollard KJ, Blackshear PJ, Mackman N, Dean JL, Boothby M, Haskard DO. Iqbal MB, et al. Among authors: dean jl. Blood. 2014 Dec 4;124(24):3646-55. doi: 10.1182/blood-2014-07-588046. Epub 2014 Oct 7. Blood. 2014. PMID: 25293769 Free PMC article.

8

The p38 MAPK pathway inhibits tristetraprolin-directed decay of interleukin-10 and pro-inflammatory mediator mRNAs in murine macrophages.

Tudor C, Marchese FP, Hitti E, Aubareda A, Rawlinson L, Gaestel M, Blackshear PJ, Clark AR, Saklatvala J, Dean JL. Tudor C, et al. Among authors: dean jl. FEBS Lett. 2009 Jun 18;583(12):1933-8. doi: 10.1016/j.febslet.2009.04.039. Epub 2009 May 3. FEBS Lett. 2009. PMID: 19416727 Free PMC article.

9

The control of inflammation via the phosphorylation and dephosphorylation of tristetraprolin: a tale of two phosphatases.

Clark AR, Dean JL. Clark AR, et al. Among authors: dean jl. Biochem Soc Trans. 2016 Oct 15;44(5):1321-1337. doi: 10.1042/BST20160166. Biochem Soc Trans. 2016. PMID: 27911715 Free PMC article. Review.

10

Gain-of-Function Mutation of Tristetraprolin Impairs Negative Feedback Control of Macrophages In Vitro yet Has Overwhelmingly Anti-Inflammatory Consequences In Vivo.

O'Neil JD, Ross EA, Ridley ML, Ding Q, Tang T, Rosner DR, Crowley T, Malhi D, Dean JL, Smallie T, Buckley CD, Clark AR. O'Neil JD, et al. Among authors: dean jl. Mol Cell Biol. 2017 May 16;37(11):e00536-16. doi: 10.1128/MCB.00536-16. Print 2017 Jun 1. Mol Cell Biol. 2017. PMID: 28265004 Free PMC article.

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