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Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase.
Merlot AM, Shafie NH, Yu Y, Richardson V, Jansson PJ, Sahni S, Lane DJR, Kovacevic Z, Kalinowski DS, Richardson DR. Merlot AM, et al. Among authors: lane djr. Biochem Pharmacol. 2016 Jun 1;109:27-47. doi: 10.1016/j.bcp.2016.04.001. Epub 2016 Apr 6. Biochem Pharmacol. 2016. PMID: 27059255
Anti-plasmodial activity of aroylhydrazone and thiosemicarbazone iron chelators: effect on erythrocyte membrane integrity, parasite development and the intracellular labile iron pool.
Walcourt A, Kurantsin-Mills J, Kwagyan J, Adenuga BB, Kalinowski DS, Lovejoy DB, Lane DJ, Richardson DR. Walcourt A, et al. J Inorg Biochem. 2013 Dec;129:43-51. doi: 10.1016/j.jinorgbio.2013.08.007. Epub 2013 Aug 26. J Inorg Biochem. 2013. PMID: 24028863 Free PMC article.
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