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Conjugation of curcumin-loaded lipid nanoemulsions with cell-penetrating peptides increases their cellular uptake and enhances the anti-inflammatory effects in endothelial cells.
Simion V, Stan D, Constantinescu CA, Deleanu M, Dragan E, Tucureanu MM, Gan AM, Butoi E, Constantin A, Manduteanu I, Simionescu M, Calin M. Simion V, et al. J Pharm Pharmacol. 2016 Feb;68(2):195-207. doi: 10.1111/jphp.12513. Epub 2016 Jan 8. J Pharm Pharmacol. 2016. PMID: 26748549
VCAM-1 directed target-sensitive liposomes carrying CCR2 antagonists bind to activated endothelium and reduce adhesion and transmigration of monocytes.
Calin M, Stan D, Schlesinger M, Simion V, Deleanu M, Constantinescu CA, Gan AM, Pirvulescu MM, Butoi E, Manduteanu I, Bota M, Enachescu M, Borsig L, Bendas G, Simionescu M. Calin M, et al. Eur J Pharm Biopharm. 2015 Jan;89:18-29. doi: 10.1016/j.ejpb.2014.11.016. Epub 2014 Nov 28. Eur J Pharm Biopharm. 2015. PMID: 25438248 Free article.
544 results