Fujiwara R - Search Results

1

Cadmium and arsenic override NF-κB developmental regulation of the intestinal UGT1A1 gene and control of hyperbilirubinemia.

Liu M, Chen S, Yueh MF, Fujiwara R, Konopnicki C, Hao H, Tukey RH. Liu M, et al. Among authors: fujiwara r. Biochem Pharmacol. 2016 Jun 15;110-111:37-46. doi: 10.1016/j.bcp.2016.04.003. Epub 2016 Apr 6. Biochem Pharmacol. 2016. PMID: 27060662 Free PMC article.

2

Glucose induces intestinal human UDP-glucuronosyltransferase (UGT) 1A1 to prevent neonatal hyperbilirubinemia.

Aoshima N, Fujie Y, Itoh T, Tukey RH, Fujiwara R. Aoshima N, et al. Among authors: fujiwara r. Sci Rep. 2014 Sep 11;4:6343. doi: 10.1038/srep06343. Sci Rep. 2014. PMID: 25209391 Free PMC article.

3

Role of extrahepatic UDP-glucuronosyltransferase 1A1: Advances in understanding breast milk-induced neonatal hyperbilirubinemia.

Fujiwara R, Maruo Y, Chen S, Tukey RH. Fujiwara R, et al. Toxicol Appl Pharmacol. 2015 Nov 15;289(1):124-32. doi: 10.1016/j.taap.2015.08.018. Epub 2015 Sep 2. Toxicol Appl Pharmacol. 2015. PMID: 26342858 Free PMC article. Review.

4

Isothiocyanates induce UGT1A1 in humanized UGT1 mice in a CAR dependent fashion that is highly dependent upon oxidative stress.

Yoda E, Paszek M, Konopnicki C, Fujiwara R, Chen S, Tukey RH. Yoda E, et al. Among authors: fujiwara r. Sci Rep. 2017 Apr 19;7:46489. doi: 10.1038/srep46489. Sci Rep. 2017. PMID: 28422158 Free PMC article.

5

Developmental hyperbilirubinemia and CNS toxicity in mice humanized with the UDP glucuronosyltransferase 1 (UGT1) locus.

Fujiwara R, Nguyen N, Chen S, Tukey RH. Fujiwara R, et al. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5024-9. doi: 10.1073/pnas.0913290107. Epub 2010 Mar 1. Proc Natl Acad Sci U S A. 2010. PMID: 20194756 Free PMC article.

6

Reduced expression of UGT1A1 in intestines of humanized UGT1 mice via inactivation of NF-κB leads to hyperbilirubinemia.

Fujiwara R, Chen S, Karin M, Tukey RH. Fujiwara R, et al. Gastroenterology. 2012 Jan;142(1):109-118.e2. doi: 10.1053/j.gastro.2011.09.045. Epub 2011 Oct 6. Gastroenterology. 2012. PMID: 21983082 Free PMC article.

7

Glucuronidation of drugs and drug-induced toxicity in humanized UDP-glucuronosyltransferase 1 mice.

Kutsuno Y, Itoh T, Tukey RH, Fujiwara R. Kutsuno Y, et al. Among authors: fujiwara r. Drug Metab Dispos. 2014 Jul;42(7):1146-52. doi: 10.1124/dmd.114.057083. Epub 2014 Apr 24. Drug Metab Dispos. 2014. PMID: 24764149 Free PMC article.

8

Glucuronidation of drugs in humanized UDP-glucuronosyltransferase 1 mice: Similarity with glucuronidation in human liver microsomes.

Kutsuno Y, Sumida K, Itoh T, Tukey RH, Fujiwara R. Kutsuno Y, et al. Among authors: fujiwara r. Pharmacol Res Perspect. 2013 Oct;1(1):e00002. doi: 10.1002/prp2.2. Epub 2013 Sep 3. Pharmacol Res Perspect. 2013. PMID: 25505556 Free PMC article.

9

Expression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse Brain.

Kutsuno Y, Hirashima R, Sakamoto M, Ushikubo H, Michimae H, Itoh T, Tukey RH, Fujiwara R. Kutsuno Y, et al. Among authors: fujiwara r. Drug Metab Dispos. 2015 Jul;43(7):1071-6. doi: 10.1124/dmd.115.063719. Epub 2015 May 7. Drug Metab Dispos. 2015. PMID: 25953521 Free PMC article.

10

Nicotine regulates the expression of UDP-glucuronosyltransferase (UGT) in humanized UGT1 mouse brain.

Sakamoto M, Itoh T, Tukey RH, Fujiwara R. Sakamoto M, et al. Among authors: fujiwara r. Drug Metab Pharmacokinet. 2015 Aug;30(4):269-75. doi: 10.1016/j.dmpk.2015.04.004. Epub 2015 May 7. Drug Metab Pharmacokinet. 2015. PMID: 26210671 Free PMC article.

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