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Evaluation of the analgesic effect of 4-anilidopiperidine scaffold containing ureas and carbamates.
Monti L, Stefanucci A, Pieretti S, Marzoli F, Fidanza L, Mollica A, Mirzaie S, Carradori S, De Petrocellis L, Schiano Moriello A, Benyhe S, Zádor F, Szűcs E, Ötvös F, Erdei AI, Samavati R, Dvorácskó S, Tömböly C, Novellino E. Monti L, et al. Among authors: erdei ai. J Enzyme Inhib Med Chem. 2016 Dec;31(6):1638-47. doi: 10.3109/14756366.2016.1160902. Epub 2016 Apr 11. J Enzyme Inhib Med Chem. 2016. PMID: 27063555 Free article.
Exploring the first Rimonabant analog-opioid peptide hybrid compound, as bivalent ligand for CB1 and opioid receptors.
Mollica A, Pelliccia S, Famiglini V, Stefanucci A, Macedonio G, Chiavaroli A, Orlando G, Brunetti L, Ferrante C, Pieretti S, Novellino E, Benyhe S, Zador F, Erdei A, Szucs E, Samavati R, Dvrorasko S, Tomboly C, Ragno R, Patsilinakos A, Silvestri R. Mollica A, et al. J Enzyme Inhib Med Chem. 2017 Dec;32(1):444-451. doi: 10.1080/14756366.2016.1260565. J Enzyme Inhib Med Chem. 2017. PMID: 28097916 Free PMC article.
Biological evaluation and molecular docking studies of AA3052, a compound containing a μ-selective opioid peptide agonist DALDA and d-Phe-Phe-d-Phe-Leu-Leu-NH2, a substance P analogue.
Kowalczyk A, Kleczkowska P, Rękawek M, Kulik K, Lesniak A, Erdei A, Borics A, Martin C, Pawlik K, Lipkowski AW, Benyhe S, Makulska-Nowak H, Ballet S, Bujalska-Zadrozny M. Kowalczyk A, et al. Eur J Pharm Sci. 2016 Oct 10;93:11-20. doi: 10.1016/j.ejps.2016.07.009. Epub 2016 Jul 14. Eur J Pharm Sci. 2016. PMID: 27423260
New opioid receptor antagonist: Naltrexone-14-O-sulfate synthesis and pharmacology.
Zádor F, Király K, Váradi A, Balogh M, Fehér Á, Kocsis D, Erdei AI, Lackó E, Zádori ZS, Hosztafi S, Noszál B, Riba P, Benyhe S, Fürst S, Al-Khrasani M. Zádor F, et al. Among authors: erdei ai. Eur J Pharmacol. 2017 Aug 15;809:111-121. doi: 10.1016/j.ejphar.2017.05.024. Epub 2017 May 11. Eur J Pharmacol. 2017. PMID: 28502630
Novel opioid-neurotensin-based hybrid peptide with spinal long-lasting antinociceptive activity and a propensity to delay tolerance development.
Frączek K, Ferraiolo M, Hermans E, Bujalska-Zadrozny M, Kasarello K, Erdei A, Kulik K, Kowalczyk A, Wojciechowski P, Sulejczak D, Sosnowski P, Granica S, Benyhe S, Kaczynska K, Nagraba L, Stolarczyk A, Cudnoch-Jedrzejewska A, Kleczkowska P. Frączek K, et al. Acta Pharm Sin B. 2020 Aug;10(8):1440-1452. doi: 10.1016/j.apsb.2020.04.014. Epub 2020 May 1. Acta Pharm Sin B. 2020. PMID: 32963942 Free PMC article.
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