LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption.
Luo J, Yang Z, Ma Y, Yue Z, Lin H, Qu G, Huang J, Dai W, Li C, Zheng C, Xu L, Chen H, Wang J, Li D, Siwko S, Penninger JM, Ning G, Xiao J, Liu M.
Luo J, et al. Among authors: li c, li d.
Nat Med. 2016 May;22(5):539-46. doi: 10.1038/nm.4076. Epub 2016 Apr 11.
Nat Med. 2016.
PMID: 27064449